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Follow on Google News | AnaSpec Releases Rabbit Anti-human Cathelicidin LL-37 Polyclonal AntibodyRabbit Anti-human Cathelicidin LL-37 polyclonal antibody was raised against a synthetic peptide from a sequence found within 134-170 amino acid residues (LL-37) of the LL-37 precursor human cationic antimicrobial protein, hCAP-18.
By: AnaSpec EGT Group Antimicrobial peptides are ancient and potent weapons of the innate immunity of all life forms (1–4). In mammals, defensins and cathelicidins are the two major families of antimicrobial peptides. While several cathelicidins were found in animals such as sheep, cow, and pig, only one cathelicidin was identified in humans (5). The precursor proteins of the cathelicidin family share a highly conserved N-terminal “cathelin” For more information, please visit https://www.anaspec.com/ Reference 1. Boman, H. G. (1995) Annu. Rev. Immunol.13, 61-92 2. Sambhara, S., and Lehrer, R. I. (2007) Expert Rev Anti Infect Ther.5, 1-5 3. Hancock, R. E. W. (2001) Lancet. Infect. Dis. 1, 156-164 4. Zasloff, M. (2002) Nature 415, 389-395 5. Zanetti, M. (2005) Curr. Issues Mol. Biol. 7, 179-196 6. Pütsep, K., et al. (2002) Lancet 360, 1144-1149 7. Nizet, V., et al. (2001) Nature414, 454-457 8. Lee, P.H., et al. (2005) Proc. Natl. Acad. Sci. U. S. A.102, 3750-3755 9. Cirioni, O., et al. (2006) Antimicrob. Agents Chemother. 50, 1672-1679 10. Bucki, R., et al. (2007) Eur. Respir. J.29, 624-632 AnaSpec, EGT Group AnaSpec, EGT Group is a leading provider of integrated proteomics and genomics solutionsTM for worldwide life science research. AnaSpec offers expertise in peptides, detection reagents, antibodies, assay kits, amino acids, oligonucleotides, and qPCRs. AnaSpec carries a broad product line of biochemicals and reagents for basic research, high-throughput screening and drug discovery. AnaSpec also provides premier custom services including peptide synthesis, antibody production, assay development, fluorescent dyes, and oligonucleotide synthesis. AnaSpec is certified to ISO 9001:2008. For more information visit www.anaspec.com # # # AnaSpec, Inc. is a leading provider of integrated proteomics solutions™ for worldwide life science research. AnaSpec offers expertise in three primary technologies: End
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