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AnaSpec Launches Industry’s First Assay for Measuring Matriptase Activity
A sensitive, long wavelength fluorimetric assay kit for measuring the activity of Matriptase, a protease implicated in carcinogenesis, is now commercially available.
The SensoLyte® Rh110 Matriptase Assay Kit provides a convenient assay for screening of Matriptase inhibitors and activators or for continuous assay of Matriptase activity using a highly sensitive fluorogenic substrate. Upon Matriptase cleavage, this substrategenerates the Rh110 (Rhodamine 110) fluorophore which has a bright green fluorescence and can be detected at excitation/emission=
Matriptase (also known as MT-SP1, ST14, TADG-15 and epithin) is a trypsin-like protease from the family of type II transmembrane serine proteases. The spectrum of known Matriptase substrates includes extracellular matrix proteins, cell adhesion molecules, ion channels, growth-factor-
To read more, https://www.anaspec.com/
1. Welman, A. et al. PLOS One7, e34182 (2012).
2. List, K. et al. Mol Med 12, 1-3(2006).
3.Quimbar, P. et al. J Biol Chem 288, 13885 (2013).
AnaSpec, EGT Group is a leading provider of integrated proteomics and genomics solutionsTM for worldwide life science research. AnaSpec offers expertise in peptides, detection reagents, antibodies, assay kits, amino acids, oligonucleotides, and Takyon™ qPCR MasterMixes. We carry a broad product line of biochemicals and reagents for basic research, high-throughput screening (HTS) and drug discovery. AnaSpec also provides premier custom services including peptide synthesis, antibody production, assay development, fluorescent dyes, and oligonucleotide synthesis. AnaSpec is certified to ISO 9001:2008.
For more information visit www.anaspec.com