FerroFarRed - An Ion Indicator for the Specific Detection of Fe2+

Intracellular Fe2+ can react with hydrogen peroxide, thereby producing the hydroxyl radical, a reactive oxygen species (ROS). Excessive ROS causes oxidative stress, resulting in cancer and neurodegenerative diseases.
 
 
Reaction Mechanism of FerroFarRed
Reaction Mechanism of FerroFarRed
 
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Reactive Oxygen Species

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Biotech

Location:
Göttingen - Lower Saxony - Germany

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GöTTINGEN, Germany - Dec. 10, 2018 - PRLog -- FerroFarRed (also known as SiRhoNox-1 or ER-SiRhoNox) is a fluorescent probe,manufactured by Goryo Chemical, Japan, distributed in Europe by MoBiTec GmbH, Germany. FerroFarRed specifically detects labile iron (II) ions (Fe2+) and is known to react with Fe2+ only, separately from other metal ions. Upon reaction with Fe2+ it irreversibly turns into a far-red fluorescent substance. FerroFarRed mainly localizes inside the endoplasmic reticulum (ER). It can also be used with a flow cytometer equipped with a red laser.

Features of FerroFarRed:

Target: Labile iron (Fe2+)
Cell Permeability: Yes
Absmax:: 646 nm
FLmax (nm): 662 nm
Fluorescence: Irreversible
Cytotoxicity: FerroFarRed shows almost no cytotoxicity at concentrations of up to 100 μM (~20 times that of generally used concentrations).

Goryo Chemical is a leading manufacturer of next generation fluorescent probes and research chemicals.

FerroFarRed and all other Goryo Chemical  products can be ordered from MoBiTec: http://www.mobitec.com

Contact info@mobitec.com for more information and bulk pricing options.

About MoBiTec GmbH

MoBiTec GmbH
(Goettingen, Germany) is a privately held company (founded in 1987) that offers research tools for molecular and cell biology. Products include DNA vectors for cloning and expression, cell transfection reagents and cell culture tools, immobilized and soluble enzymes, products for genomics and proteomics research, numerous antibodies and recombinant proteins, superior fluorescence reagents and kits, affinity chromatography products, as well as general laboratory equipment.

In parallel to its own product lines, MoBiTec distributes products from international companies in Germany. MoBiTec products are distributed worldwide, in Germany from their home office, in other countries by distributors.

Contact
MoBiTec GmbH, Lotzestr. 22a, 37083 Goettingen,
Germany, info@mobitec.com, www.mobitec.com
***@mobitec.com
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Tags:Reactive Oxygen Species
Industry:Biotech
Location:Göttingen - Lower Saxony - Germany
Subject:Products
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