Pluribead and Plurispin: The Game-Changer in Peripheral Whole Blood Analysis

EL CAJON, Calif. - June 8, 2023 - PRLog -- Peripheral whole blood (PWB) is a vital biological sample utilized in numerous medical research investigations, such as identifying diseases, developing drugs, and creating treatments. Red blood cells, white blood cells, and platelets are just a few of the various cell types found in the blood.

Among the white blood cells, peripheral blood mononuclear cells (PBMCs) are especially significant since they have a critical role in the immune system. Nevertheless, isolating these cells from the intricate mixture of blood components requires an effective method of cell separation like antibody cell separation.

A Brief on Peripheral Whole Blood

Peripheral whole blood is a blood sample collected from a peripheral vein, usually from the arm. It is a complex mixture of various components, including red blood cells, white blood cells, and platelets, suspended in a liquid called plasma. The blood is collected in tubes containing anticoagulants, which prevent the blood from clotting.

What are the Components of PBMCs

Peripheral blood mononuclear cells (PBMCs) are a group of white blood cells, including lymphocytes, monocytes, and dendritic cells. They play a crucial role in the immune system and are involved in the recognition and elimination of pathogens and infected cells. PBMCs are essential for medical research, as they can be used to investigate immune responses to various diseases and treatments.

Antibody Cell Separation for Peripheral Whole Blood Analysis

Isolating PBMCs from whole blood is essential in medical research, as it allows for the investigation of immune responses to diseases and treatments. Antibody cell separation is a technique used to separate specific cell types from the complex mixture of blood components. This technique uses antibodies that specifically bind to the surface markers of the target cells, allowing for their separation from the rest of the blood components.

Using the Right Antibody Cell Separation Method

Several methods are available for antibody cell separation, including positive selection and negative selection. Positive selection involves using antibodies that specifically bind to the target cells, allowing for their isolation, while negative selection involves using antibodies that bind to non-target cells, allowing for the isolation of the target cells. The choice of antibody cell separation method depends on the research question, the target cell type, and the downstream analysis.

Pluribead and Plurispin are cell separation technologies used directly from whole blood, buffy coat, or cord blood. What makes our products unique is their ability to offer high purity, sample viability, and throughput, which eliminates the need for additional purification steps. Our products do not use harsh magnetic fields or fast-moving liquids that could potentially harm cell health and physiology.

For efficient and reliable antibody cell separation tools, choose Uberstrainer, a leading provider of high-quality cell separation products and services.

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