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Isolating Neutrophil Granulocytes: Pluribeads as a Powerful Cell Separation Tool
Neutrophil granulocytes play a crucial role in the human body's immune response. Antibody cell separation using PluriBead and PluriStrainer enables researchers to isolate and study these cells' functions in greater detail.
By: Asteeri Infotech
In this blog, we will explore what neutrophil granulocytes are, how they function, and how they can be separated from other types of cells using various cell separation techniques, including antibody cell separation.
Neutrophil granulocytes are the most common type of white blood cells, accounting for about 60-70% of all white blood cells in the human body. They are produced in the bone marrow and are released into the bloodstream, where they circulate for several hours before migrating to the site of infection.
How do Neutrophil Granulocytes Function?
The main function of neutrophils is to detect and destroy harmful pathogens, such as bacteria and viruses, in the body. When a pathogen enters the body, neutrophils are attracted to the site of infection by chemical signals, such as cytokines and chemokines, which are produced by the infected cells.
Once they reach the site of infection, neutrophils use several mechanisms to destroy the pathogen. These include phagocytosis, the process of engulfing and digesting the pathogen, and the release of enzymes and other proteins that can kill the pathogen.
Cell Separation Techniques for Neutrophil Granulocytes
PluriBead is an innovative technology for cell separation that does not require magnetic components. The PluriBeads with target cells are passed through a strainer, and the beads with target cells remain on top while the unwanted cells pass through.
Once the beads are detached, the target cells are ready for further use. This process is simple and efficient, making it ideal for various research applications.
The PluriStrainer is a sterile sieving tool used to separate cell aggregates or obtain single-cell suspensions. It supports filtration and can be used at low pressure when paired with a Connector Ring.
PluriStrainer can be used with a funnel for large sample volumes and can be stacked to allow filtration with various mesh sizes. It can also be inverted to recover sieved material.
With the use of our innovative antibody cell separation techniques pluribead, researchers and clinicians can perform cell enrichment and separation of cells to further study the functions and characteristics of neutrophil granulocytes, and advance medical knowledge and treatment in various areas.