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Follow on Google News | Patent Application Highlights AlbuVoid™ in Cell-based Drug Toxicity AssaysBy: Biotech Support Group Narain, Niven Rajin, Rangaprasad Sarangarajan, and Vivek K. Vishnudas. "Interrogatory cell-based assays for identifying drug-induced toxicity markers." U.S. Patent Application No. 16/180,446. (http://www.freepatentsonline.com/ The lack of reliable tools that can help with predicting toxicity early in drug development is partly to blame for a 90% attrition of potential compounds entering clinical development, 30% of which is owing to poor clinical safety. Cardiotoxicity particularly is a leading cause of drug withdrawal. The invention described is useful for identifying markers associated with drug-induced toxicity. The patent application states "In one embodiment, the cells can be cultured in serum containing medium: The volume of the medium can be reduced using 3 k MWCO Vivaspin columns (GE Healthcare Life Sciences), then can be reconstituted with 1×PBS (Invitrogen) "I are very pleased to see that AlbuVoid™ was referenced for the proteomic analysis of cell culture. As we do not use immunoaffinity, separations are efficient across all species" states Swapan Roy, Ph.D., President and Founder of Biotech Support Group. For more information on AlbuVoid™, go to: http://www.biotechsupportgroup.com/ For more information on the BSG complete line of Albumin & IgG Removal products, visit: https://www.biotechsupportgroup.com/ About Biotech Support Group LLC Converging with cultural and technological disruptions forthcoming in healthcare, Biotech Support Group develops methods for cost effective and efficient sample prep essential for these expanding markets.For more information, go to http://www.biotechsupportgroup.com Contact: Matthew Kuruc 732-274-2866, mkuruc@biotechsupportgroup.com (mailto:sales@ End
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