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Importance of Edotoxin Testing in Hemodialysis PROCEDURE
Many renal disease patients depend on dialysis procedures, The Challenges in Hemodialysis is to produce large quantity of cost effective high purity water and is to avoid occurrence of endotoxin related reactions
necessarily all those present. Disinfection does not eliminate endotoxin, it is stable, it is not easily destroyed by sanitizers , Only ultrafiltration removes endotoxin.
The LAL assay is the method recommended for endotoxin testing by the most Pharmacopoeias, and is widely used the pharmaceutical industry.
All the established techniques (gel-clot, turbidimetric and chromogenic)
The LAL gel-clot test and Chromogenic Endpoint assay can be perfomed very easily in a dialysis unit. The suppliers of the LAL reagent will normally provide training in the testing and validation procedures.
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