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Novartis’ Lead Discovery Informatics Head Featured Speaker at CHI’s Structure-Based Design Event
In silico Lead Finding through Holistic Understanding of Screening Data from Multiple Approaches
Dr. Glick’s presentation entitled “In silico Lead Finding through Holistic Understanding of Screening Data from Multiple Approaches” is scheduled Friday, June 8 at 3:45-4:15 p.m. Understanding of biochemical, biophysical, pathway and functional information is critical for decision making and hypothesis generation in drug discovery. Dr. Glick will discuss the in silico approaches to support this challenge. For example, design of bio-diverse compound libraries and intentional targeting of a specific phenotype. Dr. Glick will describe how the data should be mined and visualized to enable understanding of the molecular mechanism of action and prioritize the right chemical matter for a chemistry program.
Dr. Glick’s current research focus is the application of chemometric and systems chemical biology approaches to bridge the phenotype-target and target-lead gaps in drug discovery. Prior to that, he was a trained as postdoc in the area of computational chemistry in the University of Oxford, UK. He is the author of over 40 scientific papers in peer reviewed journals and 6 patents (see publicationslist.org/
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