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Follow on Google News | 10 Key Questions Answered at Drug Design 2015In just a few weeks, SMi’s 14th annual conference on Advances and Progress in Drug Design, will open its doors to gather scientific leaders and industry KOLS from the drug design arena.
By: SMi Group Ltd 1. Compound Design and Analysis – How is this done using integrated chemical and biological information? 2. How has structure based design been crucial for the identification of PDE2 inhibitors? 3. What computational approaches are there for calculating mutation frequencies and predicting mutation probabilities for sequence residue sites? Learn to create focused mutant libraries for protein engineering in a presentation led by the President and CEO from Chemical Computing Group, Paul Labute. 4. What are the key challenges in biotherapeutics discovery and how is structural information useful in facing these challenges? 5. How can Novartis show us that the conformation of the DFG motif is tightly correlated with the propensity of helix-C displacement? 6. How have computational and predictive tools matured for the application of drug discovery? Join the debate in our panel discussion led by Uppsala University, Janssen and Chemical Computing Group. 7. How can we successfully apply ligand-based and structure based computational approaches for the rational design of novel GPCR antagonists? 8. How do you build a robust technology pipeline for robust fragment based drug discovery? Learn the keys to successful fragment based drug design with a focus on orthogonality, protein preparations and structural information. 9. How has structural biology advanced? Sanofi explain the fundamentals and structure based design of various novel kinase inhibitors. 10. How can we use chemical and biological information for compound selection and prioritisation? Further information is available online at http://www.smi- Advances & Progress in Drug Design 16th and 17th February 2015 Marriott Regents Park Hotel, London UK http://www.smi- About SMi Group: Established since 1993, the SMi Group is a global event-production company that specializes in Business-to- End
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