MoBiTec to Offer EBI's Human Anti-PEth Autologous IgG ELISA for Alcohol-Related Biomarker Detection

GÖTTINGEN, Germany - Jan. 20, 2015 - PRLog -- Human Anti-PEth Autologous IgG ELISA 96-well ELISA Assay for Detection of Autologous PEth IgG antibodies

Ethanol (EtOH) has multiple effects on humans and other animals. Alcohol addiction and organ damage are active areas of research with a need for research reagents and tools. Phosphatidylethanol (PEth) is a direct metabolite of EtOH and has been described as a long-lived biomarker for alcohol ingestion. It is possible that PEth is involved in the neurological, protective, and harmful effects of alcohol, but the mechanisms are still being explored.

Autologous anti-PEth antibodies are found in lower abundance in serum from heavier drinkers. Evaluation of serum samples of varying consumption habits has demonstrated a high degree of correlation with ingested alcohol. Measuring these autologous anti-PEth IgG levels may serve as an effective biomarker in monitoring alcohol use.

Echelon Bioscience’s Human Anti-PEth Autologous IgG ELISA is a direct assay in which the signal is proportional to the amount of autologous anti-PEth IgG contained in the sample. The serum (or plasma) sample is added to a PEth-coated plate for binding. A peroxidase-linked secondary detector and colorimetric substrate are used to detect the amount of anti- PEth antibody bound to the plate. The colorimetric signal is read at absorbance 450 nm and is directly proportional to the amount of autologous anti-PEth IgG in the sample.

The Kit includes:

• Anti-PEth Detection Plate
• Anti-PEth IgG Standard
• Sample Diluent
• Secondary Detector
• Secondary Diluent
• TMB Solution
• 1 N H2SO4 Stop Solution
• PBS Tablets
• Microtiter Plate Seals

Assay Notes
INTENDED USE: THIS PRODUCT IS FOR RESEARCH USE ONLY AND THERFORE NOT INTENDED FOR CLINICAL OR DIAGNOSTIC USE.

For details please check:

http://www.mobitec.com/cms/products/bio/09_ivd/Anti_PEth_...

MoBiTec offers products manufactured by Echelon Biosciences, USA, to its customers throughtout Europe.

Echelon Biosciences Incorporated (EBI) was incorporated under the laws of the state of Utah as Echelon Research Laboratories, Inc. on October 3, 1997. Initially, EBI was formed from a project under the Center for Cell Signaling, a State of Utah Center of Excellence, with the aim to further the science of lipid cell signaling and critical metabolic enzymes, which provide new and viable targets for the development of potential drugs and diagnostics for cancer, diabetes, inflammation, infections, and cardiovascular disease.

MoBiTec GmbH (Goettingen, Germany) is a privately held company (founded in 1987) that offers research tools for molecular and cell biology. Products include DNA vectors for cloning and expression, cell transfection reagents and cell culture tools, immobilized and soluble enzymes, products for genomics and proteomics research, numerous antibodies and recombinant proteins, superior fluorescence reagents and kits, affinity chromatography products, as well as general laboratory equipment.

In parallel to its own product lines, MoBiTec distributes products from international companies in Germany. MoBiTec products are distributed worldwide, in Germany from their home office, in other countries by distributors.