Aortic Valve Size Determines the Degree of Valve Calcification in Severe Aortic Stenosis

KREMS, Austria - March 12, 2025 - PRLog -- Recent research from Karl Landsteiner University of Health Sciences (KL Krems) provides important new insights into how aortic valve size is associated with the degree of valve calcification in severe aortic stenosis (AS).

Historically, the severity of AS has been assessed using aortic valve calcification (AVC) scores, which were interpreted differently for men and women due to observed differences in calcification levels between the sexes. However, research led by Prof. Julia Mascherbauer, Head of the Department of Internal Medicine 3 at St. Pölten University Hospital (a KL Krems teaching and research centre), offers new insights. It shows that when adjusting for valve size, the amount of calcification required to trigger severe AS was more directly linked to the size of the aortic valve annulus (the fibrous ring supporting the valve), rather than sex.

Scientific Contact

Prof. Dr. Julia Mascherbauer

Karl Landsteiner University of Health Sciences

Division of Internal Medicine 3

University Hospital St. Pölten

Dunant-Platz 1

3100 St. Pölten / Austria

T +43 2742 9004 - 12541

E julia.mascherbauer@stpoelten.lknoe.at

W https://www.kl.ac.at

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More info here: https://kris.kl.ac.at/en/publications/association-of-aortic-valve-size-with-the-degree-of-aortic-valve--4 (https://www.prd.at/)