The Scoop whether Selective Androgen Receptor Modulators(SARMs) work as Function Promoting Therapy

While steroidal SARMs have been around since the 1940s, a number of nonsteroidal SARMs that do not serve as substrates for CYP19 aromatase or 5α-reductase,act as full agonists in muscle and bone and as partial agonists in prostate are in development
LAWRENCEVILLE, Ga. - Aug. 20, 2021 - PRLog -- The differing interactions of steroidal and nonsteroidal compounds with AR contribute to their unique pharmacologic actions. Ligand binding induces specific conformational changes in the ligand binding domain, which could modulate surface topology and protein-protein interactions between AR and coregulators, resulting in tissue-specific gene regulation. Preclinical studies have demonstrated the ability of SARMs to increase muscle and bone mass in preclinical rodent models with varying degree of prostate sparing. Phase I trials of SARMs in humans have reported modest increments in fat-free mass.

The last decade has witnessed unprecedented discovery effort to develop selective androgen receptor modulators (SARMs) that improve physical function and bone health without adversely affecting the prostate and cardiovascular outcomes.

While many results out there are certainly impressive, it's important to note that everyone will respond differently to SARMs. Our biology is different, down to each individual human being, so it's impossible to predict how much muscle you'll gain and how much fat you'll lose with 100% accuracy.

That being said, most users can expect to gain at least 10 pounds of muscle from a SARMs cycle, if not even more. Many users report gaining up to 30 pounds of muscle, particularly from stronger SARMs  such as YK11 (, although this still has to be verified in a scientific study.


SARMs hold promise as a new class of function promoting anabolic therapies for a number of clinical indications, including functional limitations associated with aging and chronic disease, frailty, cancer cachexia, and osteoporosis.
Author; US National Library of Medicine

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Platinum Muscle Nutrition specializes in SARMs sports nutrition (, offering a high-quality line of SARMs for Bodybuilding, weight loss, strength and muscle gain. Every batch of their SARMs are 3rd party verified, so you know that they are at least 99% pure, verified by an independent laboratory.

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