QSPainRelief - €6 million EU-funded research project on better treatment of chronic pain kicks off

10 European institutions collaborate for the next 5 years to help patients suffering from chronic pain with novel combinational treatments
MUNICH - Feb. 21, 2020 - PRLog -- Chronic pain severely reduces the patients' quality of life, their ability to work, and their socio-economic contribution in society. 20% of Europeans suffer from chronic pain, and up to 60% of these patients don't receive effective treatment. It is crucial to help affected individuals.

In the 5-year-long EU-funded QSPainRelief project, world-leading experts on chronic pain, pharmacology, pharmacogenomics, personalized medicine, systems biology, and in silico modeling join forces to develop novel, personalized, and effective combinational treatments of existing medications.

The overarching goal is to identify alternative combinational treatment paradigms, with improved analgesia (pain relief) and reduced adverse effects via a mechanism-based Quantitative Systems Pharmacology (QSP) approach, using algorithms and advanced in silico technologies, and then validate the most promising combinational medication paradigms in preclinical models, in healthy volunteers, and in clinical practice.

QSPainRelief consortium

Alma Mater Studiorum – Università di Bologna (UNIBO), Bologna, Italy
Cliniques Universitaires Saint-Luc (CUSL), Bruxelles, Belgium
concentris research management gmbh (concentris), Fürstenfeldbruck, Germany
In Silico Biosciences, Inc. (ISB), Lexington, MA, United States
PD-value B.V. (PD-VALUE), Houten, The Netherlands
Stichting Centre for Human Drug Research (CHDR), Leiden, The Netherlands
Universitat Autònoma de Barcelona (UAB), Barcelona, Spain
Universitat Pompeu Fabra (UPF), Barcelona, Spain
Université Catholique de Louvain (UCL), Louvain-la-Neuve, Belgium
Universiteit Leiden (ULEI), Leiden, The Netherlands



Prof. Dr. Liesbeth de Lange
Scientific Coordinator
+31 (0) 71 527 6330

Dr. Nina Donner
Dissemination Manager
+49 (0) 8141 6252 8584

Dr. Sara Stöber
Project Manager
+49 (0) 8141 6252 8573


This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No. 848068. This press release reflects only the view of the author or authors (scientific coordinator, dissemination manager, and translating personnel), and the European Commission is not responsible for any use that may be made of the information it contains. Reproduction is authorized provided the source is acknowledged.

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