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Screen for KEAP1:Nrf2 Inhibitors with BPS Bioscience’s Exclusive KEAP1:Nrf2 Assay Kit
BPS Bioscience, Inc. (BPS) is now offering a KEAP1:Nrf2 Inhibitor Screening Assay Kit
The cytoprotective genes activated by Nrf2 encode proteins that provide the cell with protection from reactive oxygen species (ROS) and a number of other dangers. The protective proteins include conjugating enzymes, antioxidant enzymes, anti-inflammatory proteins, repair proteins, and others. Given the protective role of Nrf2 gene activation, scientists are searching for therapeutics that can inhibit KEAP1:Nrf2 interaction, thereby activating ARE-associated genes. This is especially important in the case of cancer, where ROS are well-known to be a major etiological factor in disease onset and progression.
BPS is the first company to offer an easy-to-use, high throughput screening platform to aid in the discovery of small molecule inhibitors of KEAP1:Nrf2 binding. The KEAP1:Nrf2 Inhibitor Screening Assay Kit joins a portfolio that also includes purified KEAP1 protein, an ARE Reporter Kit, and an ARE Reporter Cell Line, allowing researchers to use both cell-based and cell-free systems to meet their particular Nrf2 antioxidant pathway research needs. To learn more about these products, please visit BPS Bioscience’s website at http://bpsbioscience.com/
About BPS Bioscience
BPS Bioscience, Inc. is a leading manufacturer of recombinant proteins and assay kits for life science and drug discovery research. In addition to the KEAP1 and Nrf2 products, BPS offers Acetyltransferases, Bromodomains, HDACs, Histone Demethylases, Methyltransferases, Kinases, Phosphatases, Phosphodiesterases, Poly ADP Ribose Polymerases (PARPs), and Protease enzymes and assay kits. BPS also provides custom protein expression, biochemical and cell-based assays, and compound screening and profiling services. Headquartered in San Diego, California, BPS has provided products and services to pharmaceutical companies and academic institutes in over 45 countries worldwide. By being at the forefront of technology development, BPS provides innovative, high quality life science products and services in a timely manner to help our customers accelerate drug discovery and development for the treatment of human diseases.
Visit BPS’s website for more information: