GRAPE SEED EXTRACT (Vitis vinifera), Dr. Abhay Kumar Pati, Best Nutrition, Hayward, CA USA

July 11, 2010 - PRLog -- GRAPE SEED EXTRACT
(Vitis vinifera), Dr.Abhay Kumar Pati, CEO, Biotechayur, Odisha, India

ORIGIN
Europe

PART OF PLANT USED
Seed

DESCRIPTION
Grape seed extract is an antioxidant-rich extract, especially high in bioflavonoids, which is used for fighting free radicals and maintaining capillary health. It is very similar to pine bark extract, with a high content of proanthocyanidins. These are found in many foods, but freezing, cooking and canning deactivate them.
Grape seed extract is used for its free radical-fighting capabilities, and for a variety of conditions related to capillary health and permeability. It is synergistic with vitamin C, which is more potent and absorbed more rapidly when used together with proanthocyanidins.
Free radicals do damage in the capillaries in two ways. They inactivate a compound called a 1-antitripsin, whose role is to restrain the enzymes that break down collagen, elastin and hyaluronic acid. They also turn fats in the cell membranes rancid by lipid peroxidation. Proanthocyanidins protect both the 1-antitripsin and the lipids by neutralizing the specific types of free radicals most likely to damage them, and may also directly inhibit the damaging enzymes. Collagen, elastin and hyaluronic acid make up much of the inner wall and supporting matrix of the capillaries. When they are in good shape the capillaries stretch to let red blood cells through the tight places and do not let the fluids in the blood leak out.
Proanthocyanidins (also known as leucoan-thocyanidins) are a form of polyphenol, which is in turn a form of bioflavonoid. Proanthocyanidins are at least 15 to 25 times more powerful than vitamin E in neutralizing the iron and oxygen species free radicals that attack lipids.

TRADITIONAL AND OTHER THERAPEUTIC USES
•    poor distribution of microcirculatory blood flow in the brain and heart
•    altered capillary fragility and permeability, especially in diabetes mellitus
•    chronic arterial/venous insufficiency in the extremities
•    altered platelet aggregation and other charac-teristics of blood flow in capillaries
•    breakdown in the elastic fibers of the capillaries (collagen and elastin) due to free radical and enzyme action
•    microangiopathy of the retina, edema of the lymph nodes, and varicose veins
•    cumulative effects of aging, reducing the risk of degenerative diseases

TOXICITY, CAUTIONS AND CONTRAINDICATIONS
Proanthocyanidins are almost completely non-toxic both in acute dosage and long-term use. They have no known potential for causing mutation or birth defects, and have no adverse effect on fertility, pregnancy or nursing.

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Dr.Abhay Kumar Pati, Best Nutrition Products, Inc.Hayward, California, USA and Biotechayur, Odisha, India manufacturer of a large number of bestnutrition, glutathione, ashwagandha, gymnema, diabotica, gugul, psyllium, boswella, vitamins, minerals, Chinese and Ayurvedic herbal, nutritional supplements, phytochemicals, raw materials of standardized molecules of plants and fruit extracts. Dr. Abhay Kumar Pati, is a physician, author, entrepreneur and industrialist based in the United States, having ventures across the globe. Dr.Pati states that many of our health problems and diseases can be prevented, treated well with lifestyle, food habits and nutritional supplements. Most of the fruit contain ascorbic acid, enzymes, bioflavonoids, rich in minerals like chromium, potassium, and magnesium etc as well as B vitamins to amino acids.