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CD38 (Cyclase) Inhibitor Screening Kit (Fluorometric)
A plate-based fluorometric assay designed to screen, study and characterize potential inhibitors of CD38 cyclase activity.
By: BioVision Inc
It is found on the surface of many immune cells, including plasma B cells, natural killer cells, CD4+, CD8+, etc. Elevated levels of CD38 are associated with aging, obesity, diabetes, heart disease, asthma, inflammation and tumorigenesis etc. BioVision's CD38 (Cyclase) Inhibitor Screening Kit is a plate-based fluorometric assay designed to screen, study and characterize potential inhibitors of CD38 cyclase activity. The assay utilizes a selective CD38 substrate to generate a fluorescent signal measured at Ex/Em = 300/410 nm.
In the presence of potential CD38 cyclase inhibitors, the fluorescent signal is reduced. The assay is quick, easy, and sensitive for high-throughput screening of CD38 inhibitors. Additionally, the kit includes a CD38 Inhibitor as a control inhibitor.
Figure: Inhibition of CD38 cyclase activity by Quercetin. IC50 was calculated to be 5.2 ± 0.8 μM. Assay was performed following the kit protocol.
Storage Conditions -20ºC
USAGE For Research Use Only! Not For Use in Humans.
For more information on this Assay Kit Cat# K2102 https://bit.ly/
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