BTEC Announces New Course on Design of Experiments (DoE) Methods for Bioprocesses in December

Aug. 22, 2011 - PRLog -- The Biomanufacturing Training and Education Center (BTEC) at NC State University has announced a new course on bioprocessessing analysis and optimization beginning in December (12/6 - 12/8).

The course will take place on BTEC's facility on Centennial Campus.

COURSE NAME
Introduction to Design of Experiments (DoE) for Bioprocess Analysis and Optimization

DATE
Tuesday, December 6th  - Thursday, December 8th,  2011

REGISTRATION
You can register for this course through BTEC's online registration system.

WHY SHOULD YOU ATTEND
To learn the fundamental principles of Design of Experiments (DoE) methods applied to analysis and optimization of bioprocesses.  DoE is critical to defining the design space for a process, which is central to the quality by design concepts presented in the ICH Guideline for Pharmaceutical Development Q8(R2).  This class will stress the application of DoE methods through the use of statistical software and bioprocess case studies. Students will be engaged in hands-on laboratory activities involving planning and execution of fermentation experiments looking at the effects of factors such as medium components, temperature, and dissolved oxygen on growth and product formation.

ATTEND AND YOU WILL LEARN
•   Statistical background and basic concepts in DoE; statistical concepts such as hypothesis testing, confidence intervals, statistical models and Analysis of Variance (ANOVA);
•   How to design, conduct and analyze experimental designs for the characterization and optimization of bioprocesses: factorial, fractional factorial and response surface designs;
•   How to interpret outputs of experimental design software, for example normal probability, interaction, contour and residual analysis plots or ANOVA tables for factorial or surface response models.

WHO SHOULD ATTEND
•   The course is targeted at all those interested in bioprocess development and optimization, particularly those new to the DoE techniques, including:
•   Bioprocess development scientists and engineers;
•   Process validation staff interested in defining operating ranges and attribute specification;
•   Other professionals with previous hands-on bioprocess experience who want to learn about  DoE.


TO REGISTER
web address - - go.ncsu.edu/facility_solutions

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Centennial Campus is an award-winning a research park and campus owned and operated by NC State University.