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Who first described ADDISON’S DISEASE ?
Addison's disease is a rare endocrine or hormonal disorder resulting from primary adrenal insufficiency. The disease is characterized by weight loss, muscle weakness, fatigue, hypotension and increased skin pigmentation
By: Ailesbury Media
Thomas Addison (1793-1860) English Physician
Thomas Addison was born in Long Beaton, near Newcastle in 1793, the same year that Marie Antoinette was found guilty of treason and was beheaded on the guillotine. He chose a remarkably similar career path to Hodgkins (Hodgkin’s Disease) and Bright (Bright’s Disease), graduating from Edinburgh University (1815), and then moving back to London to pursue a medical career at Guy’s Hospital for the Incurables (1820). This hospital was founded in 1726, mainly as an overflow hospital for the neighbouring St Thomas's, which was working beyond its capacity. It maintained an emphasis on materia medica and medical treatment rather than on surgery, which remained the St Thomas's speciality. Addison was appointed assistant physician to the hospital in 1824, and lecturer in charge of materia medica three years later. It was 1827, the same year that Ludwig Beethoven died in Vienna following complications of pneumonia and dropsy.
Of passing interest is the fact that Addison like Beethoven, suffered from severe depression, developed deafness and was a brilliant teacher. But the similarity ends there. In 1802, Beethoven wrote the famous "Heiligenstä
He was the first doctor to describe circumscribed scleroderma, which is still known as Addison’s keloid in some parts of the world. He was also the first doctor to show that pneumonia occurred in the alveolar tissue and not in the interstitial cells. He described the progressive dysfunction of the adrenal gland associated with changes in brain tissue. This condition was later researched by the Austrian neurologist Schilder who noted loss of the myelin sheath surrounding nerve cells in the brain and the condition became known as Adrenoleukodystrophy or Addison –Schilder Disease.
Addison jumped to his death in 1860, the same year that Senator William Gwin of California and William H. Russell, of Missouri businessman bought 400 fast horses, hired 80 riders, and established the Pony Express Service.
Who am I?
South African Physician who graduated from Edinburgh and served with the RAMC in Africa during the First World War. In 1937 he became Professor of Medicine in Cairo on the advice of Sir Alexander Fleming. He died in London in 1959 and is remembered for giving his name to an autosomal nephritis associated with nerve deafness.
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Dr. Patrick Treacy is Medical Director of Ailesbury Clinics Ltd. He is Chairman of the Irish Association of Cosmetic Doctors. He is a Medical Advisor to the website Consulting Rooms. He wrote a Medical History series in 1999 for the Irish Medical TImes