What is the Neuromatrix of Pain?

COLORADO SPRINGS, Colo. - May 3, 2025 - PRLog -- The neuromatrix of pain is a network of neuronal pathways and circuits that respond to sensory (nociceptive) stimulation. ​​ It is a widely distributed neural network in the brain that generates characteristic patterns of nerve impulses, known as "neurosignature" patterns, in response to pain. ​ These patterns are responsible for the multidimensional experience of pain and can be triggered by various inputs, including tactile sensations. ​ The neuromatrix theory of pain suggests that pain is not solely caused by tissue injury or damage but rather is a complex experience produced by specific patterns of neural activity within this network. ​ The neuro matrix includes regions such as the somatosensory cortex, insular cortex, anterior and posterior cingulate cortices, prefrontal cortex, and thalamus. ​ It is involved in the perception, modulation, and interpretation of pain signals, as well as the cognitive, emotional, and motor aspects of pain. ​ Understanding the neuromatrix of pain has important implications for developing non-pharmacological and non-invasive pain therapies that target these neural pathways and circuits to reduce pain severity and interference. ​

What Percentage of Patients Reported Less Usage of Oral Medications after 14 Days?

82% of patients reported "less" or "a lot less" usage of oral medications after 14 days. ​

What is the Primary Pain Complaint of the Patients in the Study?

The primary pain complaint for the patients in the study is musculoskeletal pain, specifically myofascial/musculoskeletal pain, which was indicated by 36.5% of the patients (54 out of 148). ​

What Kind of Pain does the VTT Embedded Pain Patch Target?
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