Mcl-1L Cytoplasmic Domain Human Recombinant

SAN DIEGO - June 7, 2024 - PRLog -- Mcl-1L Cytoplasmic Domain Human Recombinant

Mcl-1L Cytoplasmic Domain Human Recombinant is a high quality member of the Bcl-2 family of proteins, which play a key role in regulating apoptosis (programmed cell death) and cell survival. The cytoplasmic domain of Mcl-1L is a specific region of the protein that is involved in its cellular functions. This recombinant protein can be used in research to study the function and regulation of Mcl-1L, as well as its interactions with other proteins involved in cell survival and apoptosis. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Mcl-1L Cytoplasmic Domain Human Recombinant
Catalog number: B2016818
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 µg
Molecular Weight or Concentration: 36 kDa
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -80°C
Keywords: Bcl-2-like Protein 3, EAT/Mcl-1, Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1, Mcl-1 Long Isoform
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Kim JH, Bae J. MCL-1ES induces MCL-1L-dependent BAX- and BAK-independent mitochondrial apoptosis PLoS One. 2013 Nov 18;8(11):e79626.
2: Fukumoto T, Iwasaki T, Okada T, Hashimoto T, Moon Y, Sakaguchi M, Fukami Y, Nishigori C, Oka M. High expression of Mcl-1L via the MEK-ERK-phospho-STAT3 (Ser727) pathway protects melanocytes and melanoma from UVB-induced apoptosis Genes Cells. 2016 Feb;21(2):185-99.

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