Mouse Biospecimen Management at University of California (Davis)
By: Krishagni Solutions
Tumor samples are surgically resected from participants consenting to the U54 study and implanted to mouse models in MBSR (Mouse Biology Shared Resources). The specimen is allowed to grow in the mouse in a sterile controlled environment and is sent back to UCD for QA (Immunohistochemistry and KI67 staining).
The data is recorded in OpenSpecimen throughout the process. OpenSpecimen has a highly configurable user interface that can be designed as per the study's needs. It is possible to configure studies to record both human and animal biospecimen data in the same instance.
Using OpenSpecimen's reporting interface, it's straightforward to retrieve data for these specimens/mouse models or the U54 participants. (See the images of the reports.)
"We could not have tracked the outgoing U54 participant specimens and the incoming U54 PDX models without OpenSpecimen's high degree of configurability. Data entry is smooth and straightforward. For easy access to data, I have set up pivot tables showing the number of specimens per PDX model plus tumor site and passage," said Irmgard Feldman, Biorepository Manager at the Department of Pathology and Laboratory Medicine at UC Davis.
Mouse Biology Program at UC Davis