HemogloBind™ Cited in Pesticide Toxicology Study of Post-Mortem Changes in Blood

By: Biotech Support Group
 
MONMOUTH JUNCTION, N.J. - Jan. 23, 2021 - PRLog -- Biotech Support Group reports on a journal article describing the simplicity and efficiency of their HemogloBind™ sample preparation technology for the analysis of the pesticide methomyl, and its Hemoglobin derivatives. The citation is:

Yamagishi, Yoshikazu, Hirotaro Iwase, and Yasumitsu Ogra. "Post-Mortem Changes of Methomyl in Blood with Hemoglobin." (https://pubs.acs.org/doi/10.1021/acs.chemrestox.0c00472) Chemical Research in Toxicology.

Methomyl is a widely used pesticide that has been detected in many fatal cases of accidental exposure or suicide. Forensic toxicologists have been baffled that the blood methomyl concentration in persons who have died of methomyl poisoning is much lower than the expected concentration in blood. In this study, the researchers considered specific methomyl hemoglobin adducts detected by liquid chromatography quadrupole time-of-flight mass spectrometry (LC-Q/TOF-MS). To help isolate Hemoglobin, the article states "Hb was separated with HemogloBind in accordance with the manufacturer's instructions." The authors conclude that one Hemoglobin derivative, the W-adduct could be used as a biomarker of methomyl poisoning.

"I am very pleased that our users have found still another application for HemogloBind™, this time in the isolation of Hemoglobin for more in-depth analysis. Its simple protocol and compatibility with liquid chromatography quadrupole time-of-flight mass spectrometry (LC-Q/TOF-MS) makes this possible." states Swapan Roy, Ph.D., President and Founder of Biotech Support Group.

For more information visit: HemogloBind™ product page, at https://www.biotechsupportgroup.com/HemogloBind-Hemoglobin-Depletion-From-Hemolyzed-p/h0145.htm

For more information on all of our Hemoglobin Removal Products, visit:
https://www.biotechsupportgroup.com/Hemoglobin-Removal-s/312.htm

About Biotech Support Group LLC

Converging with cultural and technological disruptions forthcoming in healthcare, Biotech Support Group develops methods for cost effective and efficient sample prep essential for these expanding markets. Following a tiered business strategy, the company continues its growth in the consumable research products area supporting the rapidly expanding installation of LC-MS instrument and computational infrastructure. For this market, key products include: AlbuVoid™ and AlbuSorb™ for albumin depletion, Cleanascite™ for lipid adsorption, HemogloBind™ and HemoVoid™ for hemoglobin removal, and NuGel™ for functional proteomics. From these innovations, the company has acquired knowledgebase and biomarker intellectual property assets that support discoveries of protein markers from blood, with special emphasis on early detection and personalized medical decisions for cancer patients. For more information, go to http://www.biotechsupportgroup.com.

For Business Development, contact: Matthew Kuruc 732-274-2866, mkuruc@biotechsupportgroup.com (mailto:sales@biotechsupportgroup.com)

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Tags:Blood
Industry:Biotech
Location:Monmouth Junction - New Jersey - United States
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