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Research Article Cites HemoVoid™ in Fish Red Blood Cell Proteome Study
By: Biotech Support Group
Puente-Marin, Sara, et al. "In Silico Functional Networks Identified in Fish Nucleated Red Blood Cells by Means of Transcriptomic and Proteomic Profiling (http://www.mdpi.com/
Nucleated red blood cells (RBCs) of fish have, in the last decade, been implicated in several immune-related functions, such as antiviral response, phagocytosis or cytokine-mediated signaling. Label-free shotgun proteomic analyses were carried out for in silico functional pathway profiling of rainbow trout RBCs. The article states "The cytosolic fraction, approximately 300 μL, was depleted of hemoglobin using HemoVoidTM kit (Biotech Support Group, Monmouth Junction, NJ, USA), in accordance with the manufacturer's instructions"
"This article illustrates that our proteomic enrichment products work very efficiently for all species, even non-mammals, as they do not rely on antibodies. The ability to enrich for the underlying sub-proteome from the cytosolic fraction of red cells is a unique feature of HemoVoid™. That LC-MS/MS proteome profiling identified 1,770 proteins, where 724 proteins had more than 2 PSMs,demonstrates its usefulness in proteomic investigations"
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About Biotech Support Group LLC
Converging with cultural and technological disruptions forthcoming in healthcare, Biotech Support Group develops methods for cost effective and efficient sample prep essential for these expanding markets. Following a tiered business strategy, the company continues its growth in the consumable research products area supporting the rapidly expanding installation of LC-MS instrument and computational infrastructure. For this market, key products include: AlbuVoid™ and AlbuSorb™ for albumin depletion, Cleanascite™
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