New Report Provides Key Insight to Alzheimer's Disease

Nov. 12, 2009 - PRLog -- Piribo, the online destination for business intelligence for the biotech and pharmaceutical industry, has added a new report analysing the market for Alzheimer's disease.

“Alzheimer's Disease: New Drugs, Markets and Companies”, which is available at /bit.ly/2HHicS, reports that with nearly eight million sufferers from this condition in the seven major markets of the world and anticipated increases in the future - Alzheimer's disease remains a challenge in management.

The 505 page report highlights that considerable research is in progress to understand the pathomechanism of the disease and find a cure. The only drugs approved currently are acetylcholinesterase inhibitors but they do not correct the basic pathology of the disease, beta amyloid deposits and neurofibrillary tangles.

Early diagnosis of Alzheimer's disease is an important first step in management. Several biomarkers in cerebrospinal fluid, blood and urine can detect the disease. They provide a valuable aid to the clinical examination and neuropsychological testing which are the main diagnostic methods supplemented by brain imaging. Genotyping, particularly of ApoE gene alleles is also useful in the evaluation of cases and planning management.

Authors of the report note that the current management of Alzheimer's disease is reviewed and it involves a multidisciplinary approach. Acetylcholinesterase inhibitors are mostly a symptomatic treatment but some claims are made about a neuroprotective effect.

Currently the only approved neuroprotective therapy in is memantine. Management of these patients also require neuroleptics for aggressive behaviour and antidepressants.
There is an emphasis on early detection at the stage of mild cognitive impairment and early institution of neuroprotective measures. In addition, the value of mental exercise in delaying the onset of Alzheimer's disease is being recognised.

“Alzheimer's Disease: New Drugs, Markets and Companies” is available from Piribo. For more information go to: http://www.piribo.com/publications/diseases_conditions/al...

Piribo product ID: JAI00042

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About Piribo.
Piribo (http://www.piribo.com/publications/diseases_conditions/al...) is a UK-based independent online store supplying business information on the pharmaceutical and biotechnology industries. The website now carries over 17,000 English language titles including, market reports, studies and books and is the UK’s largest online biopharma information store. Subscribers receive a free monthly newsletter and email alerts on new titles in their areas of interest. The company was established in 2004.