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Follow on Google News | Noldus unveils new tools for behavioral testing of rodent models of autismAt the annual meeting of EU-AIMS in Paris, France, Noldus Information Technology presented a new suite of tools for behavioral testing of rodent models of autism.
By: Noldus Information Technology bv Noldus’ new suite for behavioral testing of rodent models of autism consists of three tightly integrated software tools: a video tracking system for automatic recording of movement and body orientation (EthoVision XT), a system for automatic detection of ultrasonic vocalizations (UltraVox XT), and a software package for observational coding and multimodal analysis (The Observer XT). Using a common time basis and seamless data integration, these tools allow researchers to analyze the temporal and spatial correlation between visible behavior, acoustical communication and brain activity acquired with EEG sensors, within a single software environment with an intuitive user interface. Researchers can now study how behavior and communication differ between wild type and knockout mouse lines, and how these processes are modified by drugs. The system was developed by Noldus Information Technology in close collaboration with neuroscientists at the Brain Center Rudolf Magnus, University Medical Center Utrecht, in the context of EU-AIMS. The system is used for the integrated analysis of behavior, (EEG) brain activity, and vocalizations during mouse social interaction. In a social recognition paradigm, the researchers in Utrecht investigate the neurobiological mechanisms underlying the capacity of mice to discriminate between novel and familiar conspecifics. The newly developed system allows them to quantify behavior, vocalizations and brain activity simultaneously and as a function of the animal’s focus with respect to location and interaction with the other mice. EU-AIMS, short for “European Autism Interventions: Noldus Information Technology (founded in 1989, currently 130 employees) develops and delivers innovative software and hardware solutions for the measurement and analysis of behavior. Scientists in more than 85 countries use them to advance their research, product development, training, and education. Noldus has offices across Europe, North America, and China and is represented by a worldwide network of distributors. Press contact: Sandra Thoomes-Wildschut Noldus Information Technology BV Wageningen, The Netherlands www.noldus.com info@noldus.nl End
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