First ZAP-X® Radiosurgery System Installed in French Public Hospital Institut Hartmann

Institut H. Hartmann and AP-HP hospitals inaugurate France's first public hospital ZAP-X installation at Centre de Radiochirurgie Paris Nord, providing 600 public sector patients annually access to advanced brain radiosurgery.
By: INSTITUT H. HARTMANN
 
PARIS - Nov. 16, 2025 - PRLog -- PARIS, France

Institut de Radiothérapie et de Radiochirurgie H. Hartmann and AP-HP hospitals Lariboisière, Beaujon, and Saint-Louis have installed the first ZAP-X cranial radiosurgery system in a French public hospital. This pioneering installation at Centre de Radiochirurgie Paris Nord represents a significant milestone in democratizing access to advanced radiosurgery technology.

Revolutionary Technology Enters Public Healthcare

The ZAP-X system represents the first major innovation in cranial radiosurgery in 50 years. As the world's first self-shielded radiosurgery platform, it eliminates the need for traditional concrete bunkers, featuring a unique gyroscopic architecture that generates hundreds of converging mini-beams of high-energy X-rays with submillimeter precision.

The system includes integrated high-resolution imaging with automatic repositioning every 45 seconds and real-time dosimetric monitoring. Any deviation between planned treatment and actual delivery triggers automatic session interruption, ensuring optimal safety.

Clinical Applications and Patient Benefits

The ZAP-X system treats multiple intracranial pathologies including brain metastases, benign tumors such as meningiomas and schwannomas, rare tumors, vascular malformations, and functional indications including trigeminal neuralgia and certain epilepsy cases.

Treatment sessions last under 30 minutes without anesthesia, incision, or hospitalization. Patients wear a custom-fitted mask for head immobilization and can return home immediately after treatment, typically requiring one to three sessions for complete treatment. The technology's reduced penumbra minimizes radiation exposure to healthy tissues, resulting in fewer side effects.

Expert Collaboration and Research

The project unites leading medical expertise from public and private sectors. Dr. Marc Bollet and Dr. Nathaniel Scher from Institut Hartmann work closely with Professor Christophe Hennequin (radiotherapy, AP-HP), Dr. François Nataf (neurosurgery, AP-HP), and Professor Sébastien Froelich.

Enhanced Patient Access

The ZAP-X installation at Lariboisière Hospital is the second in France and the first in a public hospital setting. No other French public university hospital currently operates a ZAP-X system, positioning AP-HP as a pioneer in this technology's clinical utilization and scientific development.

Zap-X presentation : https://radiotherapie-hartmann.fr/specialites/radiochirur...

About Institut de Radiothérapie et de Radiochirurgie H. Hartmann

Institut H. Hartmann, part of the ELSAN-Seny group, specializes in advanced radiotherapy and radiosurgery treatments with a strong commitment to innovation and technology access for patient care. Website: https://radiotherapie-hartmann.fr/

Contact Information

Institut de Radiothérapie et de Radiochirurgie H. Hartmann
4 rue Kléber
CS 90004
92 309 Levallois-Perret Cedex
Tél : 01 47 57 67 10-

Contact
Pr. Alain Toledano
Dr Nathaniel Scher
***@adgency360.com
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