Is RA genetic? Dr. Amitabha Saha Shares The Risk Factors

KOLKATA, India - Sept. 16, 2025 - PRLog -- Rheumatoid arthritis is a chronic autoimmune disease that causes inflammation in the synovium membrane, the lining of the joints. Over time, the inflammation leads to permanent joint damage, pain, stiffness and loss of mobility.

While RA can affect anyone, there are certain risk factors that make an individual susceptible to the condition. Many patients also have a common question: " Can RA be inherited?"

According to Dr. Amitabha Saha, one of the most trusted names in rheumatoid arthritis treatment in Kolkata, the answer is not that straightforward, but it is crucial to understand for your health risks.

"Genetics do play an important role in increasing the risk of RA, " says Dr. Amitabha Saha.

"In fact, the latest research shows that the risk of developing RA is linked to a combination of genetics, family history, and environmental triggers," he further added.

Certain genetic markers, particularly within the HLA (human leukocyte antigen) system, such as the HLA-DR4 gene, are more common in people with RA.

If you have a first-degree relative (like a parent or sibling) with RA, your chances of developing the condition are two to three times higher than those of the general population.

"Having a genetic predisposition does not mean that you are likely to have RA. It only means that you are at a higher risk, though lifestyle factors also matter," says Dr. Saha.

In addition to genetics, Dr. Amitabha Saha lists other factors which increase the likelihood of developing RA.

Smoking – A major environmental trigger, especially for those who are already genetically predisposed.

Gender – Women are two or three times more prone to developing RA than men.

Age – RA often starts between the ages of 30 and 60, but it can occur at any age.

Obesity – Excess weight adds stress to joints and increases inflammation.

Hormonal influences – Hormones like estrogen may influence RA risk.

Infections and gut health – Some viral or bacterial infections may trigger autoimmune responses in susceptible individuals.

If you fall under any of these categories, make sure to seek rheumatoid arthritis treatment in Kolkata for expert guidance and advice.

Dr. Amitabha Saha offers comprehensive and personalised treatment for patients suffering from RA.

"My goal is not just to manage pain. Instead, it emphasises preventing further joint damage and improving the overall quality of life, " says Dr. Saha.

To get the best outcomes, it is advisable to go for early screening and intervention.

Know more: https://www.dramitabhasaha.com/rheumatoid-arthritis-sympt...