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Follow on Google News | The Art of Neuroscience: Synaptic Transmission and Plasticity in Isolated NeuronsResearch Team at the Karl Landsteiner University of Health Sciences develops novel protocol for studying isolated pairs of hippocampal neurons. Dedicated work honoured by cover page in Bio-protocol Journal.
By: KL Krems Nerve signals are sent quickly and over long distances. This requires complex physiological activities between the ends of different nerve cells (neurons), the synapses. Here, neurotransmitters are released and bound by receptors, as well as recycled again by later uptake mechanisms. Studying this intricate interaction is difficult, as in most established experimental models neurons are interconnected with many other neurons, and activities at one synapse cannot be regarded as independent of influence by others. Furthermore, most experimental set-ups only allow the analysis of mono-directional transmission, i.e., studying only pre- or postsynaptic effects, and only between certain types of cells. Now a method developed by a team at the Division of Physiology at the KL Krems has changed all that. W https://www.kl.ac.at/ End
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