New Development on Cancer Killing Vaccines

New vaccines and injectable medications offer new options for cancer treatment. Take a look at what new options are available.
 
AUSTIN, Texas - Feb. 16, 2023 - PRLog -- Viral Infections Can Contribute To The Development Of Certain Types Of Cancer

Determining how and why different types of cancers develop in humans can be complicated.

In many cases, more than one contributing factor is involved – ranging from genetic mutations present in our DNA to exposure to pathogens or unhealthy environmental conditions.

The existence of multiple factors – plus the long development time-frame of many cancers – has proved challenging for oncologists seeking to identify why one patient receives a cancer diagnosis while another does not.

Fortunately, major advances in clinical diagnostics and genetics testing have helped researchers zero in on identifying the root cause of many cancer types.

In what may be a surprising statistic to the layperson, researchers estimate that a least a fifth of cancers can be traced back to exposure to viral pathogens, including Epstein-Barr virus (Hodgkin lymphomas), hepatitis B virus (Hepatocellular carcinoma), human papillomavirus (Cervical carcinoma), human T-cell lymphotropic virus (Adult T-cell leukemia), hepatitis C virus (Hepatocellular carcinoma), Kaposi's sarcoma herpesvirus (Kaposi's sarcoma), and Merkel cell polyomavirus (Merkel cell carcinoma).

Human Papillomavirus (HPV) Vaccine Can Lower The Risk Of Cervical Carcinoma (And More)

Once a virus is identified as a cancer-causing agent, researchers can double down on their efforts to find an effective vaccine or other clinical treatment to prevent viral exposure leading to a future cancer diagnosis.

German researcher Harald zur Hausen was co-awarded the 2008 Nobel Prize in Medicine for his work identifying the connection between HPV and cervical cancer.

The first HPV vaccine was developed at the University of Queensland in Australia and brought to market in 2006 by Merck under the brand name Gardasil.

The HPV vaccine contains inactivated L1 portions of the natural HPV virus, delivered inside hollow virus-like particles (VLPs), causing the body's immune system to mount an effective defense against the real virus upon exposure.

While the HPV vaccine is most closely associated with reducing the risk of cervical cancer, it can also reduce instances of penile and anal cancer. It may also help prevent cases of head and neck cancers, though this is still being researched.

Using A Modified Herpes Virus As A Delivery Mechanism To Treat Solid Cancerous Tumors

Researchers in London have created a genetically modified herpes virus, RP2, that during an early-stage study shows promise in the treatment of solid cancerous tumors when administered in combination with the cancer immunotherapy drug nivolumab (a PD-1 inhibitor, discussed below).

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