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Follow on Google News | Biotech Support Group presented 2 posters at 2021 Conference on Mass Spectrometry & Allied TopicsBy: Biotech Support Group A Preliminary Investigation Using Targeted LC-MS Proteomic Methods Demonstrates Unique Serum Profiles of Hospitalized SARS-CoV-2 Patients For serum samples, targeted LC-MS is challenging, mainly due to the presence of highly abundant proteins. So it becomes critical to pair target peptides to sample depletion methods to best establish differentiated profiles between samples. In this preliminary investigation, we use unique methods described here to characterize the functionality of the innate immune response in hospitalized Covid-19 patients, more precisely than current methods. High-throughput, Automated INTip™ SPE Combined with AlbuSorb™ Products for Efficient Albumin and Albumin/IgG Depletion We report here new methods to incorporate beads for depletion of Albumin, IgG and Hemoglobin, into pipette tips known as XTRaction tips or XTR tips. The XTR tip format improves ease of use and scalability to process multiple samples in parallel, utilizing 96-well plates and automated liquid handlers. The incorporated BSG beads are consumable, and not derived from immuno-affinity. "These two posters highlight the value of collaborative partners jointly working to commercialize new methods and biomarkers using novel proteomic sample prep products. The first demonstrates how we can adapt LC-MS to study the functionality of a most important regulating family of proteins - the Serpins, as they serve as central control within the innate immune response. The second demonstrates our commitment to high-throughput and automation for clinical proteomics. It is very exciting to share these developments with a dedicated group at the forefront of mass spectrometry research", states Dr. Swapan Roy, Ph.D., President and Founder of Biotech Support Group. For more information on BSG & Lawson Health Research Institute Collaborative Research Agreement, see our joint press release: https://www.biotechsupportgroup.com/ For more information on INTip™ SPE and BSG products, see our joint press release: https://www.biotechsupportgroup.com/ For more information on the BSG complete line of Albumin & IgG Removal products, visit: https://www.biotechsupportgroup.com/ For more information on the BSG complete line of Hemoglobin Removal products, visit: https://www.biotechsupportgroup.com/ About Biotech Support Group LLC For the proteomics market, key products include: AlbuVoid™ and AlbuSorb™ for albumin depletion, Cleanascite™ For Business Development, contact: Matthew Kuruc 732-274-2866 mkuruc@biotechsupportgroup.com End
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