Cancer Diagnostics: New Factor Simplifies Classification of Brain Tumours

Thanks to a team from Karl Landsteiner University of Health Sciences in Krems (Austria), standardised classification of the aggressiveness of tumours based on their shape is now possible.
By: Karl Landsteiner University of Health Sciences
KREMS, Austria - Dec. 1, 2021 - PRLog -- Objective assessment of irregularities in a tumour's shape provides a means to evaluate its aggressiveness more effectively prior to an operation. This was the key finding made by a team of physicians from Karl Landsteiner University of Health Sciences in Krems whose research focused on meningiomas, a form of tumour that affects the meningeal tissue in the brain. In a study published in the latest issue of the Journal of Neurosurgery, the research team demonstrated the high predictive value of the model they developed and named the surface factor. The model represents an objective and comparable parameter for the quantification of irregularities in tumour shape. Based on data from more than 125 patients, the study found a statistically significant correlation between a low surface factor (i.e. an irregular tumour surface) and a higher level of aggressiveness in the tumour.

Although meningiomas – tumours that develop in the meninges – are often benign, around 20% of cases are characterised by a higher degree of aggressiveness. Distinctions are drawn using the WHO classification, which grades tumours from I to III once they have been surgically removed and also determines the subsequent treatment regimen. However, pre-operative classification would be highly beneficial, as it would provide the surgeon with vital advance information on the best suited surgical strategy. A group of physicians from Karl Landsteiner University of Health Sciences in Krems (KL Krems) has now demonstrated that the factor they calculated provides precisely this type of information.

Scientific Contact

Dr. Franz Marhold

Department of Neurosurgery

University Hospital St. Pölten

Karl Landsteiner University of Health Sciences
3100 St. Pölten

T +43 2742 9004-12961


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Dr. Barbara Bauder

Kollersteig 68

3400 Klosterneuburg / Austria

T +43 664 1576350


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Location:Krems - Lower Austria - Austria
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