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Follow on Google News | Mayo Clinic Researchers Publish Critical Study: Antifibrotics Can Extend Lives for IPF PatientsHistorically, patients with idiopathic pulmonary fibrosis have grim outcomes when hospitalized. Mayo researchers discovered that antifibrotics can improve survival for up to two years
By: Three Lakes Foundation Idiopathic Pulmonary Fibrosis (IPF) is a serious lung disease that causes scarring of the lung tissue. "Idiopathic" Andrew H. Limper, MD, a pulmonologist, is an author of the study and is associate dean and director of the Kern Center for the Science of Health Care Delivery at Mayo Clinic. "To our knowledge, this is the first use of real-world data to evaluate the impact of antifibrotics on hospitalization outcomes," he said. "Our findings are unique in that we tracked patients — with and without antifibrotics — after a hospitalization event, demonstrating the role antifibrotics have in improving survival for up to two years of therapy as well as in decreasing the number of hospitalizations." The study reviewed the de-identified claims data (from a national insurance data warehouse) of nearly 3,000 patients diagnosed with IPF and admitted for a respiratory event. According to the study, it appears that while being on the IPF drugs may not improve mortality during or immediately after hospitalization, the medications did, however, show improved long-term survival following hospitalization. Historically, IPF patients have grim outcomes when hospitalized. The aim of the Mayo team's study was to determine if the drugs nintedanib and pirfenidone can reduce mortality, admission in intensive care units or the use of mechanical ventilation while in the hospital. "This study demonstrates the positive impact of these drugs for people with IPF," said Bridget Burke, associate director for Three Lakes Foundation. "They are critical therapies to incorporate in the treatment of IPF as we continue our efforts to focus on improving time to diagnosis and delivering next generation of therapies." The article, "Outcomes for hospitalized patients with idiopathic pulmonary fibrosis treated with antifibrotic medications," To download and read the article in BMC Pulmonary Medicine, visit: https://bit.ly/ End
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