New Regulator For Blood Cancer Development Identified
A research team led by physicians of the Karl Landsteiner University of Health Sciences in Krems (KL Krems) uncovers a pivotal role for a regulator protein in tumour bone marrow angiogenesis.
A specific regulatory protein significantly influences the development of tumour-inducing blood vessels in the bone marrow of blood cancer patients. Using a series of different experiments, the team identified that a transcription factor known as JunB is central for the formation of new blood vessels in the bone marrow of patients suffering from multiple myeloma (MM). The findings, which have been published in the journal Leukemia, could pave the way for novel treatment approaches for this still incurable disease.
About Karl Landsteiner University of Health Sciences
At Karl Landsteiner University of Health Sciences (KL) in Krems, the comprehensive approach to health and disease is a fundamental objective for research and teaching. With its Europe-wide recognized bachelor-master system, KL is a flexible educational institution that is tailored to the needs of students, the requirements of the labor market as well as the scientific challenges. Currently KL hosts about 600 students in the fields of medicine and psychology. The four university hospitals in Krems, St. Pölten, Tulln and Eggenburg ensure clinical teaching and research at the highest quality level. In research, KL focuses on interdisciplinary fields with high relevance to health policy - including medical technology, molecular oncology, mental health and neuroscience, as well as water quality and related health aspects. KL was founded in 2013 and accredited by the Austrian Agency for Quality Assurance and Accreditation (AQ Austria).
Priv.-Doz. Mag. DDr. Klaus Podar
Department of Internal Medicine 2
University Hospital Krems
Karl Landsteiner University of Health Sciences
3500 Krems an der Donau
T +43 2732 9004 12355