CD38 (Hydrolase) Inhibitor Screening Kit (Fluorometric)
A plate-based fluorometric assay designed to screen, study and characterize potential inhibitors of CD38 hydrolase activity.
By: BioVision, Inc.
BioVision's CD38 (Hydrolase) Inhibitor Screening Kit is a plate-based fluorometric assay designed to screen, study and characterize potential inhibitors of CD38 hydrolase activity. The assay utilizes a selective CD38 substrate to generate a fluorescent signal measured at Ex/Em = 300/410 nm. In the presence of potential CD38 hydrolase inhibitors, the fluorescent signal is reduced. The assay is quick, easy, and sensitive for high-throughput screening of CD38 inhibitors. Additionally, the kit includes a CD38 Inhibitor as a control inhibitor.
Figure: Inhibition of CD38 activity by Apigenin. IC50 was calculated to be 6.1 ± 0.1 μM. Assay was performed following the kit protocol.
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