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Butyrylcholinesterase Inhibitor Screening Kit (Colorimetric)
A rapid, reliable and 96-well plate based colorimetric assay for high-throughput screening of potential inhibitors of Butyrylcholinesterase.
By: BioVision, Inc.
BioVision's Butyrylcholinesterase Inhibitor Screening Kit is a 96-well plate based, colorimetric assay to screen potential inhibitors of BChE. The kit utilizes the ability of active human BChE enzyme to hydrolyze the BChE substrate thereby generating a yellow colored product measured by absorbance at 412 nm. As the enzyme activity is inhibited in the presence of a potent, reversible BChE inhibitor, Rivastigmine, the color formation is inhibited. The assay is adapted for a 96-well plate format and provides a rapid, simple, and reliable test for high-throughput screening of BChE inhibitors.
Figure: Inhibition of BChE activity by Rivastigmine. IC50 of Rivastigmine was calculated to be 550.9 ± 120.2 nM. Assay was performed following the kit protocol.
For more information on this assay kit Cat# K2084, Visit: https://bit.ly/
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