The HLA Gene and How It's Affecting 25% of Us
Carriers of the HLA-DR (human leukocyte antigen) gene are prone to develop chronic health issues involving systemic inflammation.
By: The Mold Guy
Proteins are the building blocks for everything in your body. Bones and teeth, hair and earlobes, muscles and blood, are all made up of proteins. Those proteins help our bodies grow, work properly, and stay healthy. As well as determining characteristics such as eye and hair colour, genes can also directly cause the risk of developing a wide range of medical conditions.
Up until now, it's been set up that generally 25% of the population is a carrier (and sufferer) of the HLA-DR gene. That is more than 80 million individuals in the United States. Hereditary investigations on specific populations currently propose that the genuine number could be anywhere in the range of 40% and 60% around the world!
Carriers of the HLA-DR (human leukocyte antigen) gene are prone to develop chronic health issues involving systemic inflammation, whether the cause is mold, Lyme disease/ other tick borne illnesses , gluten, or countless other catalysts. HLA-DR makes a person helpless against biotoxin sickness, it additionally makes detoxification very difficult.
If you happen to have the dreaded moldy genes, there will be an increased response from your innate immune system when it identifies molds or mycotoxins. The innate immune system is the initial defense from injury and infection. The innate system fires rapid inflammatory responses to foriegn invaders. The vast majority of those experiencing Chronic Inflammatory Response Syndrome (CIRS) have the HLA DR/DQ genetic mutation. In these cases, the adaptive immune system is unable to work properly. The adaptive immune system clones receptors to bind to antigen presenting cells. This basically is the defense against extracellular microbes and their toxins, like mycotoxins. This leaves your body stuck fighting mold and mycotoxins with solely it's innate immune system.
Symptoms can vary from person to person however, these are of the most most common toxic mold symptoms:
Metallic taste in the mouth
In addition to chronic inflammatory response syndrome (CIRS), mycotoxin exposure has been connected with chronic fatigue and other illnesses including allergies, asthma, mast activation cell syndrome, mitochondrial disease, pulmonary diseases, and certain rhinosinusitis.