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Research Article Cites HemoVoid™ in Biomarker Study for Parkinson's Disease
By: Biotech Support Group
The citation is:
Elhadi, Suaad Abd, et al. "α‐Synuclein in blood cells differentiates Parkinson's disease from healthy controls. (https://onlinelibrary.wiley.com/
The goal of this study was to determine whether blood cells expressing α-Synuclein can differentiate Parkinson's disease (PD) from healthy controls. The pathological hallmark of PD is the occurrence of Lewy pathology; α-Synuclein (α-Syn) being a major constituent. Growing evidence now suggests that PD is a systemic disease and that α-Syn can be detected in blood erythrocytes. As the extremely high abundance of hemoglobin from erythrocytes can often interfere with protein analysis, the article states PSer129 α -Syn & Oxidized α -Syn detection: "followed from hemoglobin clearance with HemoVoid kit (Biotech Support Group LLC,NJ, US)". The authors demonstrate the potential usefulness of blood cell α-Syn as a biomarker for PD.
Whole Blood Compartments
"We have focused our development efforts around proteomic profiling of the various blood compartments. I am very pleased to see that this article illustrates the ability to enrich for the underlying sub-proteome from the cytosolic fraction of red cells as a unique feature of HemoVoid™. That two sub-forms of α -Syn were measurable by immunoassay demonstrates its flexibility for a wide variety of applications"
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About Biotech Support Group LLC
Converging with cultural and technological disruptions forthcoming in healthcare, Biotech Support Group develops methods for cost effective and efficient sample prep essential for these expanding markets. Following a tiered business strategy, the company continues its growth in the consumable research products area supporting the rapidly expanding installation of LC-MS instrument and computational infrastructure. For this market, key products include: AlbuVoid™ and AlbuSorb™ for albumin depletion, Cleanascite™
Biotech Support Group LLC