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Follow on Google News | Will AAV Vectors Have a Role in Future Novel Gene Therapy Approaches?In the article entitled "Future of rAAV Gene Therapy: Platform for RNAi, Gene Editing and Beyond, " Paul Valdmanis and Mark Kay, Stanford University (CA), envision the advances in gene therapy that will be achievable using existing and emerging rAAV technology for the safe and efficient delivery of gene editing technologies such as CRISPR-Cas9, RNA interference and gene silencing strategies, and targeted DNA sequences for use in genome engineering. "Drs. Kay and Valdmanis envision the exciting prospect of using AAV as a platform to deliver a wide array of novel tools for genetic manipulation of the genome and of gene expression," Research reported in this publication was supported by the National Institutes of Health under Award Numbers 1R01 DK-078424 and 1R01 AI-11698. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. About the Journal Human Gene Therapy, the Official Journal of the European Society of Gene and Cell Therapy, British Society for Gene and Cell Therapy, French Society of Cell and Gene Therapy, German Society of Gene Therapy, and five other gene therapy societies, is an authoritative peer-reviewed journal published monthly in print and online. Led by Editor-in-Chief Terence R. Flotte, MD, Celia and Isaac Haidak Professor of Medical Education and Dean, Provost, and Executive Deputy Chancellor, University of Massachusetts Medical School, Human Gene Therapy presents reports on the transfer and expression of genes in mammals, including humans. Related topics include improvements in vector development, delivery systems, and animal models, particularly in the areas of cancer, heart disease, viral disease, genetic disease, and neurological disease, as well as ethical, legal, and regulatory issues related to the gene transfer in humans. Its companion journals, Human Gene Therapy Methods, published bimonthly, focuses on the application of gene therapy to product testing and development, and Human Gene Therapy Clinical Development, published quarterly, features data relevant to the regulatory review and commercial development of cell and gene therapy products. Tables of contents for all three publications and a free sample issue may be viewed on the Human Gene Therapy (http://www.liebertpub.com/ About the Publisher Mary Ann Liebert, Inc., publishers (http://www.liebertpub.com/ Mary Ann Liebert, Inc. 140 Huguenot St., New Rochelle, NY 10801-5215 www.liebertpub.com Phone: End
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