BMS has joined forces with uniQure to develop gene therapies for cardiovascular diseases

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WASHINGTON - April 7, 2015 - PRLog -- Bristol-Myers Squibb (BMS) will get exclusive access to uniQure’s gene technology platform based on a strategic collaboration between both companies to identify multiple targets in cardiovascular diseases. BMS is expected to make near-term payments of approximately $100 million to uniQure and also purchase shares in the company equaling 4.9% for at least $32 million. BMS will also acquire an additional 5.0% ownership before December 31, 2015, at a 10% premium.

By utilizing uniQure’s proprietary gene therapy program, this joint venture will focus on congestive heart failure which includes restoring the heart’s ability to synthesize S100A1, a calcium sensor and an important regulator of cardiac contractility. uniQure will manufacture all clinical and commercial supplies using its vector technologies and its industrial, proprietary insect-cell based manufacturing platform. BMS will lead development and regulatory activities, cover all research and development costs and assume sole responsibility for commercialization of all products from this collaboration.

“Bristol-Myers Squibb has an excellent and long-standing track record of success in discovering and developing treatments for cardiovascular diseases and in embracing advancing technologies for the treatment of human diseases,” said Carl Decicco, Ph.D., Head of Discovery, R&D, Bristol-Myers Squibb. “Collaborating with uniQure, a clear leader in the field with an innovative and validated gene therapy platform, further strengthens our capability to bring forward transformational new therapeutics for difficult-to-treat diseases, including cardiovascular diseases such as heart failure.”

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