News By Tag
News By Place
AstraZeneca announces top-line results from Phase III studies of antibiotic CAZ-AVI
The investigational antibiotic CAZ-AVI was studied in patients with intra-abdominal infections (cIAI).
CAZ-AVI is an investigational antibiotic consisting of cephalosporin (ceftazidime)
The Phase III studies, RECLAIM-1 and RECLAIM-2 evaluated the safety and efficacy of CAZ-AVI in hospitalized adult patients with complicated intra-abdominal infections. CAZ-AVI, administered intravenously as a two hour infusion (2000 mg / 500 mg) plus metronidazole, compared to meropenem, administered intravenously as a 30 minute infusion (1 g). The data revealed CAZ-AVI produced higher statistical significance compared meropenem. According to the company, ‘The primary endpoint was a clinical cure rate 28 to 35 days after randomization (the Test of Cure visit)’
“We are very encouraged by these results which highlight the potential for CAZ-AVI to provide a much-needed new treatment option for serious and life-threatening intra-abdominal infections, especially where antibiotic resistance poses a threat to treatment,” said Briggs Morrison, Executive Vice President, Global Medicines Development & Chief Medical Officer, AstraZeneca.
CAZ-AVI is also currently being studied to treat complicated urinary tract infections (cUTI), nosocomial pneumonia and for the treatment of cIAI and cUTI patients with ceftazidime-
CAZ-AVI is a joint collaboration with Forest Laboratories, a wholly-owned subsidiary of Actavis. AstraZeneca holds the global rights to commercialize CAZ-AVI, however , Forest Laboratories will assume the rights to market in North America
CANDIDATES WHO WANT TO BREAK INTO PHARMACEUTICAL SALES!
The CNPR is a federally trademarked certification you can earn by demonstrating the necessary knowledge in pharmacology, medical terminology, physiology, and regulations for selling pharmaceuticals. The CNPR examination is dedicated to increasing the professional level of NAPSR members and to developing meaningful and ethical standards fully accepted by both its members and members of the pharmaceutical community.
The CNPR® Program represents a level of industry achievement and a demonstrated knowledge of pharmacology, medical terminology, pharmaceutical selling guidelines, physician selling techniques and industry standards. Pharmaceutical sales candidates who have this training will differentiate themselves from other individuals looking for open positions. Upon successful completion of the training each student will receive the Certification Mark of the CNPR®. CNPR® graduates should immediately utilize the NAPSRx® Career Center to apply for pharmaceutical sales positions.
Individuals that are interested in becoming a Certified National Pharmaceutical Representative (CNPR) can contact the National Association of Pharmaceutical Sales Representatives(