BioVision Introduces Tools to Efficiently Extract, Enrich and Detect Poly-ubiquitinated Proteins

Tools to Extract, Enrich & Detect Poly-ubiquitinated Proteins.
Tools to Extract, Enrich & Detect Poly-ubiquitinated Proteins.
MILPITAS, Calif. - April 9, 2014 - PRLog -- Post-translational modification of proteins by ubiquitin plays an important role in the regulation of numerous biological processes in eukaryotes including proteasome-mediated proteolysis, autophagy, DNA damage tolerance, inflammation, apoptosis, signal transduction etc. In order to understand these processes in greater detail, there is a requirement for techniques that can purify mixtures of ubiquitin-conjugated proteins, as a prerequisite to their identification and characterization.

BioVision is very thrilled to offer multiple tools which facilitate efficient extraction, enrichment and detection of poly-ubiquitinated proteins. These tools work with multiple sample types and outperform the alternative products on market. Additionally, they are easy to use, inexpensive and give reproducible results.

Key Features and benefits:

EZEnrich™ Polyubiquitin Beads (6568-300), 300 µl:

- Facilitates quick enrichment of proteins containing at least 4 ubiquitin sub-units.

- Binding Capacity: ~ 2.06 µg/20 µl of slurry. Total Capacity: 15 enrichments with 20 µl beads each.

- Compatible with complex samples like tissue homogenates, whole cell lysates, subcellular organelles like mitochondria, endoplasmic reticulum, etc.

- Harvested samples compatible with multiple downstream applications like proteomic studies, protein ubiquitination status tests etc.

- Use for recovery of poly-ubiquitinated proteins from in vitro ubiquitination reactions.

For more information, please visit

EZDetect™ Polyubiquitin Probe (Biotin conjugated) (6569-250), 250 µl:

- Facilitates detection of poly-ubiquitinated proteins by decreasing the interference from free monomeric ubiquitin which is highly abundant in biological samples.

- Use with Western Blot, Dot Blot, Immunohistochemistry, Immunocytochemistry etc.

For more information, please visit:

EZExtract™ Polyubiquitin Buffer Kit (K6570-3), 3 components:

- Facilitates efficient extraction of polyubiquitinated proteins from cells while preserving the ubiquitination state of proteins.

- Use also as a general lysis buffer for a broad range of applications, including Western blot, ELISA, dot blot, enzymatic assays, etc.

- Harvested samples compatible with numerous downstream applications including mass spectrometry.

For more information, please visit:

UIM-UBA Fusion Protein (6571-250), (100 µg) 250 µl:

- Use as a negative control for biotin UIM-UBA in detecting polyubiquitinated proteins in cell lysate/tissue homogenate using Dot blot.

For more information, please visit:

We offer introductory and bulk discounts on all our products. Get yours by writing to

About BioVision:

BioVision, Inc. is a privately held Life Science company headquartered in the beautiful San Francisco Bay area. BioVision develops and offers a wide variety of products including assay kits, antibodies, recombinant proteins & enzymes, and other innovative research tools for studying Apoptosis, Metabolism, Cell Proliferation, Cellular Stress, Cell Damage and Repair, Diabetes, Obesity and Metabolic Syndrome, Stem Cell Biology, Gene Regulation, Signal Transduction, and more.

Venkat Bhat
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