Novel Cardiac Gene Therapy Might Be Launched Soon to Reverse Heart Failure

American researchers have successfully developed a new type of treatment
Novel Cardiac Gene Therapy and SUMO1 Gene
Novel Cardiac Gene Therapy and SUMO1 Gene
SHIRLEY, N.Y. - Nov. 15, 2013 - PRLog -- American researchers have successfully developed a new type of treatment, called SUMO1 ( gene therapy that can reverse the upcoming heart failure of large animals after injection to heart.

Now the study has entered into end stage and is expected to soon be able to enter into clinical trials.

One of the study founders said that SUMO-1 gene therapy can effectively reduce heart enlargement and significantly improve cardiac function to maintain vital signs.

Heart failure is still a major factor for elder hospitalization. In the United States each year nearly 30 million people died because of the disease.

Heart failure is a variety of syndrome that is caused by cardiac structural or functional disorders-based ventricular filling and (or) impaired ejection ability.

About Gene SUMO1

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized.

Source: Creative Biomart (, a leading biotech company that provides quality recombinant proteins, diagnostic antibodies and antigens , diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.

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