Long term use of painkillers can cause kidney cancer
There is no increased risk from taking aspirin or paracetamol, said Padma Shri and Dr B C Roy National Awardee Dr KK Aggarwal President Heart Care Foundation of India.
The mechanism through which painkillers could cause kidney disease is the inhibition of prostaglandin synthesis with resulting papillary and tubular injury, and ultimately damage to DNA.
The study analyzed data from 77,525 women in the Nurses' Health Study and from 49,403 men in the Health Professionals Follow-up Study. The risk was related to the duration of use of the painkillers. There was a decrease in the risk by 19% if the painkiller was used for less than four years. There was a 36 per cent increase in risk of kidney cancer for people who used them regularly for 4 to 10 years. The risk increased almost three times for those who used these drugs regularly for 10 years or more.
The good news is that kidney cancer is uncommon so the risk is small for average users.
Two other important causes of kidney cancer are obesity and smoking. So people on painkillers should not smoke and should also keep their weight under control to prevent kidney cancer.
About HCFI : The only National Not for profit NGO, on whose mega community health education events, Govt. of India has released two National Commemorative stamps and one cancellation stamp, and who has conducted one to one training on” Hands only CPR” of 71933 people since 1st November 2012.
The CPR 10 Mantra is – “Within 10 minutes of death, earlier the better; at least for the next 10 minutes, longer the better; compress the centre of the chest of the dead person continuously and effectively with a speed of 10x10 i.e. 100 per minute.”
Dr K K Aggarwal