New Recommendations for Standardizing Studies of Thyroid Hormone and Disease from ATA Taskforce

NEW ROCHELLE, N.Y. - Sept. 5, 2013 - PRLog -- New Rochelle, NY—Despite tens of thousands of studies in the literature on the thyroid gland, thyroid hormone, and thyroid disease, lack of standardization in study design makes it difficult to compare the results and apply them to the development of improved diagnostic and treatment approaches. A new report from the American Thyroid Association's Taskforce on Approaches and Strategies to Investigate Thyroid Hormone Economy includes 70 specific recommendations and accompanying commentaries on a range of topics. The report is available free online on the Thyroid (http://www.liebertpub.com/thy) website. Thyroid, the peer-reviewed journal from Mary Ann Liebert, Inc., publishers (www.liebertpub.com), is the official journal of the American Thyroid Association (ATA) (www.thyroid.org).

Understanding the physiology of the thyroid gland and the activity of thyroid hormone in healthy individuals and in patients with disorders such as hypothyroidism, hyperthyroidism, and thyroid cancer is essential for developing new, more effective clinical practice and therapeutic strategies. Much knowledge is gained from studying thyroid tissue and thyroid hormone in animal and cell models.

Antonio C. Bianco, University of Miami Miller School of Medicine, and Chair of the ATA Taskforce, led a team of specialists in basic thyroid research in a review of the literature to identify which experimental practices would benefit from standardization. The panel of experts then defined consensus recommendations for how best to standardize study design and experimental approaches to achieve more reproducible results, in the American Thyroid Association Guide to Investigating Thyroid Hormone Economy and Action in Rodent and Cell Models (http://online.liebertpub.com/doi/pdfplus/10.1089/thy.2013...).

“This is an outstanding and comprehensive guide for translational and basic research scientists that has filled an important gap in our thyroid research field,” says Bryan R. Haugen, MD, President of the ATA and Professor of Medicine and Pathology, Head, Division of Endocrinology, Metabolism & Diabetes, Mary Rossick Kern and Jerome H. Kern Chair in Endocrine Neoplasms Research, University of Colorado School of Medicine. “Dr. Bianco and the entire Taskforce are to be commended for developing this authoritative and extremely useful reference.”

“This is a unique compilation of detailed recommendations for performing experiments focusing on the pathophysiology of the thyroid using cell and animal models. It will guide numerous researchers how to best conduct these experiments and will lead to more standardized approaches in many laboratories worldwide,” says Peter A. Kopp, MD, Editor-in-Chief of Thyroid and Associate Professor of Medicine, Division of Endocrinology, Metabolism and Molecular Medicine, and Interim Director of the Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago.

About the Society
The American Thyroid Association (ATA) (http://www.thyroid.org) is the leading organization devoted to thyroid biology and to the prevention and treatment of thyroid disease through excellence in research, clinical care, education, and public health. ATA is an international membership medical society with over 1,600 members from 43 countries around the world. Celebrating its 90th anniversary, ATA delivers its mission through several key endeavors: the publication of highly regarded monthly journals—Thyroid, Clinical Thyroidology, and Clinical Thyroidology for Patients; annual scientific meetings; biennial clinical and research symposia; research grant programs for young investigators, support of online professional, public and patient educational programs; and the development of guidelines for clinical management of thyroid disease and thyroid cancer. The ATA has extensive online information on their website (http://www.thyroid.org) on thyroid disease and thyroid cancer for patients in both English and Spanish. The ATA website (http://www.thyroid.org) serves as the authoritative clinical resource for patients and the public who look for reliable information and physician referral on the Internet.

About the Journal
Thyroid (http://www.liebertpub.com) the official journal of the American Thyroid Association (ATA), (http://www.thyroid.org) is an authoritative peer-reviewed journal published monthly online with Open Access (http://www.liebertpub.com/openaccess/thyroid/55/) options in print. The Journal publishes original articles and timely reviews that reflect the rapidly advancing changes in our understanding of thyroid physiology and pathology, from the molecular biology of the cell to clinical management of thyroid disorders. Thyroid is expanding its comprehensive coverage of thyroid related disease, care, and research with the addition of two new components: Clinical Thyroidology (monthly) and VideoEndocrinology (quarterly). Complete tables of content and a sample issue may be viewed on the Thyroid (http:// www.liebertpub.com/thy) website.

About the Publisher
Mary Ann Liebert, Inc., publishers (http://www.leibertpub.com) is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including Diabetes Technology & Therapeutics, Journal of Women’s Health, and Metabolic Syndrome and Related Disorders. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry’s most widely read publication worldwide. A complete list of the firm’s more than 70 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers (http://www.leibertpub.com) website.