Adcetris Case Studies to be Discussed at CHI’s 2nd Annual Oncology Clinical Trials Conference

Nov. 11, 2011 - PRLog -- Cambridge Healthtech Institute today announces two new case studies to be presented on Adcetris (brentuximab vedotin) at its Second Annual Oncology Clinical Trials: Bringing Targeted & Tailored Therapy to Patient conference to be held on March 21-23, 2012 at the Moscone North Convention Center in San Francisco, CA.  

Back in August 2011, Adcetris (brentuximab vedotin) was approved under the FDA’s accelerated approval program to treat Hodgkin lymphoma (HL) and a rare lymphoma known as systemic anaplastic large cell lymphoma (ALCL). Lymphomas are cancers of the lymphatic system. Adcetris is an antibody-drug conjugate that combines an antibody and drug, allowing the antibody to direct the drug to a target on lymphoma cells known as CD30.

Case studies to be discussed:

Clinical Development of Brentuximab Vedotin: Five Remarkable Years from First Patient Treated to Accelerated Approval
Eric Sievers, M.D., Vice President, Clinical Affairs, Seattle Genetics

Observation of multiple complete remissions among advanced lymphoma patients treated in a phase one setting led Seattle Genetics to pursue paired, single-arm, registrational trials. This presentation will review the overall strategy that led to marketing registration in 2011.

Accelerated Approval of a Targeted Antibody-Drug Conjugate (ADC): Brentuximab Vedotin Case Study
Elaine S. Waller, Pharm.D., M.B.A., Senior Vice President, Regulatory Affairs, Seattle Genetics, Inc.

FDA review of the brentuximab vedotin BLAs was complex due to inclusion of two indications, the ADC technology, and an ODAC environment influenced by recent hearings on accelerated approval of oncology drugs.

Early registration discounts are available until November 18, 2011. To view the entire conference agenda and to register, please visit http://www.TriConference.com/cct

CHI's Oncology Clinical Trials conference is part of the Molecular Medicine Tri-Conference.

To inquire about sponsoring and/or exhibiting, contact Jon Stroup, 781-972-5483, jstroup@healthtech.com.

Writers and editors are encouraged to attend. To request a press pass, contact Tracey Fielding at tfielding@healthtech.com.

About Cambridge Healthtech Institute (www.chicorporate.com)

Cambridge Healthtech Institute (CHI) is the preeminent life science network for leading researchers and business experts from top pharmaceutical, biotech and academic organizations. CHI’s portfolio of products includes Cambridge Healthtech Institute Conferences, Insight Pharma Reports, Barnett International, Cambridge Marketing Consultants, Cambridge Meeting Planners and Cambridge Healthtech’s Media Group, which includes numerous e-newsletters as well as Bio-IT World magazine.

Founded in 1992, Cambridge Healthtech Institute strives to develop quality information sources that provide valuable new insights and competing points of view while offering balanced coverage of the latest developments. Basic research related to commercial implications is covered, with heavy emphasis placed on end-user insights into new products and technology as well as coverage on the strategy behind the business.

Contact:
James Prudhomme
Cambridge Healthtech Institute
781-972-5400
jprudhomme@healthtech.com