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Follow on Google News | Just Released: "Lead Generation Strategies and Technologies in Drug Development"New Pharmaceuticals research report from GBI Research is now available from Fast Market Research
Summary GBI Research has released its latest report, 'Lead Generation Strategies and Technologies in Drug Development - Emerging Techniques Such as Antisense Technology Will Allow Innovators to Minimize Costs' that provides key data, information and analysis of the major trends and developments in the drug devleopment business. The report provides a comprehensive insight into key technological developments, new approaches in lead generation and various technologies developed to accelerate it.The report also provides key alliances and collaborations in the industry to minimize costs and maximize productivity. This report is built using data and information sourced from proprietary databases, primary and secondary research and in house analysis by GBI Research's team of industry experts. ------------------------------------------------------------ Full Report Details at - http://www.fastmr.com/ ------------------------------------------------------------ Scope The scope of the report includes - * Key technological developments and new approaches including case studies. * Case studies of new technologies and their implementation by companies in drug development industry * Key drivers and restraints that have a significant impact on the market. * Competitive benchmarking of leading CROs, covering their offerings and recent deals in drug development Reasons to buy The report will enhance your decision making capability. It will allow you to - * Compare the key capabilities and models of major technology solution providers with your requirements and optimize your R&D costs * Develop market entry and market expansion strategies by identifying the key drivers and challenges in the global drug development market * Develop effective strategies to maximize the advantages through the understanding of drug development and business models. Partial Table of Contents: 1 Table of Contents 1 Table of Contents 1.1 List of Tables 1.2 List of Figures 2 Introduction 2.1 GBI Report Guidance 3 The Drug Discovery Process: Defining Lead Generation 3.1 Process of Early Preclinical Drug Discovery 3.1.1 Pre-Discovery 3.1.2 Target Identification 3.1.3 Target Validation 3.1.4 Lead Identification 3.1.5 Early Safety Tests 3.1.6 Lead Optimization 3.1.7 Preclinical Testing 3.2 Hit to Lead - Identifying Possible Structure 3.2.1 Strategies Used In Generating Potential Lead from Identified Hits 3.3 Role of Lead Generation in the Path of Drug Development 4 Lead Generation Strategies in the Pharmaceutical Industry 4.1 Massive Decline in Sales - Dependence on Blockbuster Drugs 4.2 Need to Accelerate Lead Generation Process 4.2.1 Stricter FDA Rules and Regulations for Drug Approval 4.2.2 Penetration of Aggressive Generic Companies 4.2.3 The Economic Impact of Compound Attrition at Various Stages of Lead Discovery 4.2.4 Drought in the R&D Pipeline Products (Low R&D Productivity) 4.3 HTS Solutions for ADME Testing 4.3.1 In Vitro Studies of Drug Absorption 4.3.2 In Vitro Studies of Protein Binding 4.4 Fragment-Based Drug Discovery 4.4.1 Differences Between HTS and FBDD 4.4.2 Advantages of Fragment-Based Drug Design over High-Throughput Screening 4.4.3 Applications of Mass Spectrometry in Fragment Library Screening 4.4.4 Recent Advances in Structure-Based Fragment Docking and Virtual Screening 4.4.5 Novel Strategy for the Design of a Fluorinated Fragment Library, Named LEF (Local Environment of Fluorine) 4.4.6 Ligand-Based Approach to In Silico Pharmacology 4.5 Antisense Technology as a Strategy 4.5.1 Isis Pharmaceuticals 4.5.2 CytRx Laboratories 4.6 Iterative Focused Screening as a Strategy 4.6.1 Merck Frosst Canada 5 Emerging Technology in Lead Generation 5.1 Improving High Throughput Screening 5.1.1 Overview 5.1.2 Case Study 5.1.3 Improving In Vitro Assays for HTS 5.1.4 Whole Animal Imaging and Microscopy 5.2 The Parallel Synthesis Approach 5.2.1 In Vitro Methods 5.2.2 In Silico Methods - Structure-Toxicity Relationships 5.3 Computerized Combinatorial Chemistry and 3D Molecular Modeling 5.3.1 Overview 5.3.2 Service Providers 5.3.3 Case Studies 5.4 Molecular Bioimaging 5.4.1 Overview 5.4.2 Service Providers 5.4.3 Case Study 5.5 Omics-Technology and Bioinformatics 5.5.1 Overview 5.5.2 Service Providers 5.5.3 Case Study 6 Lead Generation Now and in the Future 6.1 R&D Models: Influence on Lead Generation 6.1.1 Recent Technology Developments 6.2 A Novel Technology to Enhance Fragment-Based Drug Discovery 6.2.1 ZoBio's Target Immobilized NMR Spectroscopy Method for Fragment-Based Drugs 7 Pharmaceutical Outsourcing as a Strategy to Accelerate Lead Generation 7.1 Early Stage Drug Development Outsourcing 7.1.1 Strategic or Tactical Advantages of Outsourcing 7.1.2 Case Study 7.2 Emerging Regions in the Global Contract Research Outsourcing Market for Early Stage Drug Development 7.2.1 Latin America 7.2.2 Central and Eastern Europe (CEE) 7.2.3 India 7.2.4 China 8 Major Contract Research Organizations in Drug Discovery 8.1 Cyprotex Discovery Ltd. 8.1.1 Business Overview 8.1.2 Services 8.2 Shanghai ChemPartner 8.2.1 Business Overview 8.2.2 Services 8.3 Covance, Inc. 8.3.1 Business Overview 8.3.2 Services 8.4 Caliper Life Sciences 8.4.1 Business Overview 8.4.2 Services 8.5 GVK BIO 8.5.1 Business Overview 8.5.2 Services 8.6 Jubilant Biosys 8.6.1 Business Overview 8.6.2 Services 8.7 Advinus Therapeutics 8.7.1 Business Overview 8.7.2 Services 8.8 ITR Canada 8.8.1 Business Overview 8.8.2 Services 8.9 MD Biosciences 8.9.1 Business Overview 8.9.2 Services 8.10 PPD, Inc. 8.10.1 Business Overview 8.10.2 Services 8.11 Ricerca Biosciences, LLC 8.11.1 Business Overview 8.11.2 Services 8.12 MPI Research 8.12.1 Business Overview 8.12.2 Services 9 Lead Generation Strategies and Technologies in Drug Discovery - Appendix 9.1 Market Definitions 9.2 Abbreviations Full Table of Contents is available at: -- http://www.fastmr.com/ About GBI Research GBI Research provides industry-leading global business intelligence solutions. Their products and services help companies make better business decisions, win business and position themselves more effectively. GBI Research publishes more than 100 research reports each year across a wide range of industries. These reports draw on in-depth primary and secondary research, databases of proprietary in-house data and high quality analysis from their expert teams. GBI Research employs hundreds of highly qualified Analysts across the US, Europe and Asia. View more research from GBI Research at http://www.fastmr.com/ About Fast Market Research Fast Market Research is an online aggregator and distributor of market research and business information. We represent the world's top research publishers and analysts and provide quick and easy access to the best competitive intelligence available. For more information about these or related research reports, please visit our website at http://www.fastmr.com or call us at 1.800.844.8156. # # # Fast Market Research is an online aggregator and distributor of market research and business information. We represent the world's top research publishers and analysts and provide quick and easy access to the best competitive intelligence available. End
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