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Follow on Google News | New Market Research Report: Next-Generation Sequencing Technologies: Applications and MarketsCambridge Healthtech Institute (CHI) releases its latest Insight Pharma Report, Next-Generation Sequencing Technologies: Applications and Markets, available at InsightPharmaReports.com
By: Insight Pharma Reports Following an overview of the evolution of NGS, Next-Generation Sequencing Technologies: NGS is also becoming increasingly popular for applications once dominated by microarrays. ChIP-seq’s improved data quality compared to microarrays permits greater accuracy in identifying protein-binding DNA targets. RNA-seq provides an alternative to microarrays in assessing cell transcriptomes and is well on its way to becoming the dominant mode in transcriptomics. Although much of the benefit to date from NGS-based investigation falls in the basic research realm, a number of applied research areas are starting to show progress as well. Essentially all NGS manufacturers have intense interest in diagnostic applications, often both as supplier and participant. Collaborative programs aimed at such applications are now in progress. Several companies have focused on epigenetic assays in cancer resulting in some early commercial activity, but products have generally been slow to emerge. Personal genomics has also been slow to develop as a business area. The field remains rather controversial, with proponents looking to its brilliant possibilities and opponents emphasizing the limited value of current offerings. However, the rapid pace of NGS basic research is likely to add significant value to personal genome sequencing in the next several years. Nearer-term NGS applications with established value include aneuploidy detection, carrier screening tests for multiple Mendelian diseases, mitochondrial DNA sequencing for a number of diseases, and others. Next-Generation Sequencing Technologies: Finally, we provide conclusions and prognosticate on possible future trends in the field. Included are full transcripts of interviews we conducted with researchers and managers knowledgeable in various aspects of NGS applications. For more information, samples pages or to purchase this report, go to: http://www.insightpharmareports.com/ Related Reports: Cloud Computing in Life Sciences R&D http://www.insightpharmareports.com/ Epigenetic Drug & Diagnostic Pipelines: DNA Methylation, HDAC Inhibitors, and Emerging New Targets http://www.insightpharmareports.com/ # # # Insight Pharma Reports are written by experts in consulting and industry who collaborate with us to provide a series of reports that evaluate the salient issues in pharmaceutical technology, business, and therapy markets. End
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