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Follow on Google News | Process Safety Guide: Reducing Runaway Reaction RiskA new, free METTLER TOLEDO Process Safety Guide helps professionals working in chemical and pharmaceutical development reduce runaway reaction risk to increase process safety, limit rework, and lower related manufacturing costs.
By: www.mt.com Even though chemical manufacturing should be intrinsically safe, the Guide shows how appropriate process review is essential to maintaining reaction control, particularly when operating conditions deviate from expected norms. Predominant variables discussed include reactant accumulation, high impurity sensitivity, induction issues and inaccurate kinetic assumptions. Modeling for heat, energy accumulation, and induction is covered in depth using a semi-batch nitration reaction as an example. Because modeling reactions in practice is typically not feasible, the Guide shows how critical process safety analysis can be reduced to a number of basic properties that accurately predict maximum temperature of the synthesis reaction (MTSR) and worst-case scenario maximum attainable temperature (MAT). This data, in turn, can be depicted as a "Runaway Graph," accounting for both primary and secondary reactions. This graph can then be used to effectively redesign processes to increase reaction safety, even under unexpected, adverse conditions, using techniques such as modifying concentration/ The ultimate goal of the Process Safety Guide is to achieve desired reaction outcomes—including maximum productivity— Contact information: Mettler-Toledo International Inc. Im Langacher, Zip Code 8606 Greifensee, Switzerland E-Mail : ePublicRelations@ Phone : +41-44-944 33 85 Website : www.mt.com About Author: METTLER TOLEDO specializes in the area of precision instruments for professional use. METTLER TOLEDO laboratory instruments are used in research, scientific, drug discovery, and quality control labs, amongst many others in the pharmaceutical, chemical, food and cosmetics industries. METTLER TOLEDO comprehensive industrial solutions cover the various steps in a host of manufacturing processes at many of the same customers that laboratory serves. Solutions range from receiving raw materials through various manufacturing processes, in-line process control and end-of-line packaging control, to logistics and shipping. Increasingly, these solutions are fully integrated into the customer's IT environment, helping automate their workflows. In food retail, our offering for fresh food management ranges from receiving and pre-packaging, to in-store solutions for self-service departments, deli counters, and checkout terminals. End
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