Stemedica International and EPFL Awarded Swiss Government Grant for Diabetes and Stem Cell ResearchEPALINGES, Switzerland - Aug. 26, 2015 - PRLog -- Stemedica International, a subsidiary of Stemedica Cell Technologies, Inc. (San Diego, CA) and its academic partner, École Polytechnique Fédérale de Lausanne (EPFL) have been awarded a research grant by the Swiss Commission for Technology and Innovation (CTI). The value of the project is CHF 708,000 (approx. 750,000 USD). Using EPFL’s advanced imaging capabilities, scientists from EPFL and Stemedica International will assess the potential benefits that Stemedica’s ischemic tolerant stem cells and stem cell factors could have for millions of people suffering from Type 1 and Type 2 Diabetes.
EPFL and Stemedica International recently completed work on a 2012 CTI research grant that showed in pre-clinical studies a dramatic reduction in cerebral Abeta amyloidosis, a major neuropathological hallmark of Alzheimer’s disease. The spectacular results from this pre-clinical research along with excellent safety data from Stemedica’s Phase I safety study has recently enabled Stemedica International to receive approval from the FDA for a Phase IIa clinical trial in the United States. This trial is expected to start in late 2015. “We are pleased that we are continuing our collaboration with one of the world’s leading technical academic institutions,” EPFL has developed sophisticated imaging methods that allow for both structural and functional in vivo imaging of islets of Langerhans in the pancreas. Within each islet are several types of cells that work together to regulate blood sugar. One cell type is the beta cell. Beta cells sense sugar in the blood and release the necessary amount of insulin to maintain normal blood sugar levels. The immune system mistakenly sees beta cells as "potential danger" and destroys them, causing type 1 diabetes. The loss of these cells means the body can no longer produce insulin, the hormone required to convert food into energy for the body’s cells. In this study, a three-dimensional assessment of the islet vascularization and blood flow in non-diabetic and diabetic mouse models will be conducted without the need to inject contrast agents. Professor Theo Lasser, Head of Laboratoire d’Optique Biomedicale (LOB), EPFL, commented, “We are excited to collaborate again with Stemedica International and to apply our methods of Optical Coherent Microscopy developed at LOB, EPFL and to potentially contribute significantly to finding a cure for diabetes.” Tristan Bolmont, PhD, Stemedica International’ About Stemedica International S.A. Founded in Epalinges, Switzerland, in 2008, Stemedica International S.A. is a biotechnology company that develops therapeutic applications for the treatment and prevention of Alzheimer’s disease, vascular dementia and Diabetes. The company is a subsidiary of Stemedica Cell Technologies, Inc., a global biotechnology company that manufactures adult allogeneic stem cells. Stemedica International has an exclusive license to manufacture and distribute the parent company’s allogeneic, ischemia-tolerant mesenchymal stem cell (itMSC) and ischemia-tolerant neural stem cell (itNSC) lines and stem cell factors for Alzheimer’s disease and vascular dementia indications. The company also has Swissmedic licenses to import, export and distribute Stemedica Cell Technologies’ Key Words Stemedica, Stemedica International, biotechnology, bio-therapeutics, biologics, regenerative medicine, stem cells, adult stem cells, diabetes, EPFL Contact Stemedica International, S.A. David Cheatham, MBA Business Manager dcheatham@stemedica.com +41 (0)21 651 9050 End
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