Production Challenges for Complex Biologics: ADCs, Bispecifics and Fusion Proteins

NEEDHAM, Mass. - July 24, 2015 - PRLog -- Cambridge Healthtech Institute (CHI) released Production Challenges for Complex Biologics: ADCs, Bispecifics and Fusion Proteins Digital Course, which was recorded at the 11TH ANNUAL PEGS Boston.

The Production Challenges for Complex Biologics: ADCs, Bispecifics and Fusion Proteins Conjugates Digital Course Digital Course is available in Digital Download, Single Copy and a Site License.  This course includes 2 presentations and over 100 slides.

Agenda at a Glance:

·         Maintaining competitiveness: efficacy requirements for 2020 and beyond

·         Timelines and Risk Reduction in Biotherapeutics Discovery: 2015 Paradigms

·         Developability assessments and timing of candidate nomination

·         Stable cell line generation, tips and tricks

·         Analytical characterization, exploratory tox, MOA, and efficacy

·         Choice of chemistry, conjugation efficiency and scaleup

·         ADC Production variability yield and process optimization

·         Next generation linkers/warheads that achieve higher quality preps, better activity in vivo

·         Towards production homogeneity, and improved therapeutic index

·         Pegylation to extend product half life and analytical

·         Assessment of available technologies to produce and manufacture bispecific Ab and next generation scaffolds

·         FDA guidance for next generation products

Presentation Speakers Includes:

Christopher D. Thanos, Ph.D.Director, New Molecular Entities, Halozyme Therapeutics, Inc.

Stefan R. Schmidt, Ph.D., M.B.A. Vice President, DSP, Rentschler Biotechnology

For more information on this course, visit:

http://www.pegsummit.com/pegs_content.aspx?id=150997

About Cambridge Healthtech Institute (http://www.healthtech.com)

Cambridge Healthtech Institute (CHI), founded in 1992, is the industry leader in providing superior-quality scientific information to eminent researchers and business experts from top pharmaceutical, biotech, and academic organizations. Delivering an assortment of resources such as events, reports, publications and eNewsletters, CHI's portfolio of products include Cambridge Healthtech Institute Conferences, Barnett Educational Services, Insight Pharma Reports, Cambridge Marketing Consultants, Cambridge Meeting Planners, Knowledge Foundation and Cambridge Healthtech Media Group, which includes Bio-IT World, Clinical Informatics News, and Diagnostics World News.